3-哌啶-3-丙胺 | 35307-80-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 3-哌啶-3-丙胺
• 中文别名: 3-(哌啶-3-基)丙-1-胺
• 英文名称: 3-(γ-Aminopropyl)-piperidin
• 英文别名: 3-piperidin-3-yl-propylamine；3-piperidin-3-ylpropan-1-amine
• CAS: 35307-80-3
• 化学式: C₈H₁₈N₂
• 分子量: 142.244
• InChiKey: PBOHQKOPNYAQIX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2933399090

反应信息

• 作为反应物：
  描述：

  3-哌啶-3-丙胺 、 、 1,5-Di-(3-isopropylnorborn-2-yl)-3-pentanone 、 、 丙烯腈 以to furnish 1-(3-aminopropyl)-3-{3-[1,5-di-(3-isopropylnorborn-2-yl)-3-pentylamino]propyl}piperidine的产率得到1-(3-Aminopropyl)-3-{3-[1,5-di-(3-isopropylnorborn-2-yl)-3-pentylamino]propyl}piperidine
  参考文献：
  名称：

  Dibicyclo[3.1.1] and [2.2.1] heptyl and dibicyclo [3.1.1] and [2.2.1]

  摘要：

  新型二环[3.1.1]和[2.2.1]庚基和二环[3.1.1]和[2.2.1]庚烯基烷基多胺是有用的抗微生物剂，同时也是藻类抑制剂。它们特别适用于硬表面消毒剂以及作为添加剂添加到油井钻井泥浆、注入卤水和工业水中，以期达到细菌控制的效果。

  公开号：

  US04033748A1

文献信息

• [EN] (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS<br/>[FR] COMPOSÉS (HÉTÉRO)ARYLE CYCLOPROPYLAMINES EN TANT QU'INHIBITEURS DE LSD1
  申请人：ORYZON GENOMICS SA

  公开号：WO2013057320A1

  公开（公告）日：2013-04-25

  The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula I as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection.

  本发明涉及（杂）芳基环丙胺化合物，特别是如本文所述和定义的公式I的化合物，以及它们在治疗中的用途，例如，在治疗或预防癌症、神经疾病或状况、或病毒感染中的用途。
• NOVEL COMPOUND HAVING MULTIMER STRUCTURE OF XANTHENE DERIVATIVE, COLORING COMPOSITION, INK FOR INKJET RECORDING, METHOD OF INKJET RECORDING, COLOR FILTER, AND COLOR TONER
  申请人：FUJIFILM CORPORATION

  公开号：US20140176653A1

  公开（公告）日：2014-06-26

  There is provided a compound represented by formula (1): in formula (1), L represents a divalent to tetravalent linking group; D represents a residue obtained by removing 1 to 5 hydrogen atoms from a compound represented by formula (2); m represents an integer of 1 to 10, however, each L may be the same with or different from every other L; n represents an integer of 2 to 10, however, each D may be the same with or different from every other D; and in formula (2), each of R 4 to R 24 independently represents a hydrogen atom or a substituent, provided that formula (2) has at least one or more ionic hydrophilic groups.

  提供了一种由公式(1)表示的化合物：在公式(1)中，L代表二价到四价的连接基团；D代表通过从由公式(2)表示的化合物中去除1到5个氢原子获得的残基；m代表1到10的整数，但是，每个L可以相同也可以不同于其他L；n代表2到10的整数，但是，每个D可以相同也可以不同于其他D；在公式(2)中，R4到R24中的每一个独立地代表一个氢原子或一个取代基，前提是公式(2)至少有一个或更多的离子亲水基团。
• [EN] SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP)<br/>[FR] PYRIDONES SUBSTITUES INHIBITEURS DE LA POLY(ADP-RIBOSE) POLYMERASE (PARP)
  申请人：AVENTIS PHARMA INC

  公开号：WO2005097750A1

  公开（公告）日：2005-10-20

  The present invention discloses and claims a series of 2,3,5-substituted pyridone derivatives as defined herein. This invention also relates to methods of making these compounds. The compounds of this invention are inhibitors of poly(adenosine 5'-diphosphate ribose) polymerase (PARP) and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases, including diseases associated with the central nervous system and cardiovascular disorders.

  本发明公开并声明了一系列如下定义的2,3,5-取代吡啶酮衍生物。本发明还涉及制备这些化合物的方法。本发明的化合物是多聚腺苷酸二磷酸核糖酶（PARP）的抑制剂，因此在制药剂中特别用于治疗和/或预防各种疾病，包括与中枢神经系统和心血管疾病相关的疾病。
• Diphenyl derivatives of polyamine compounds having a piperidine moiety
  申请人：Merck & Co., Inc.

  公开号：US04079059A1

  公开（公告）日：1978-03-14

  Novel diphenyl and loweralkyl substituted diphenyl polyamines are useful antimicrobial agents, as well as algae inhibitors. They are especially useful because of their low toxicity, and as such are advantageously included as the active agent in surgical scrubs, antibacterial soaps, as preservatives in cosmetic preparations, and the like. They also can be used for topical treatment of dermatological conditions having a bacterial origin or implication such as Acne vulgaris.

  新型二苯基和低烷基取代的二苯基多胺是有用的抗微生物剂，同时也是藻类抑制剂。它们特别有用，因为它们毒性低，因此有利地包含在手术清洁剂、抗菌肥皂、化妆品制剂的防腐剂等中作为活性剂。它们还可以用于治疗细菌性皮肤病，例如痤疮等。
• Macrocyclic Benzofused Pyrimidine Derivatives
  申请人：Altenbach Robert J.

  公开号：US20080188452A1

  公开（公告）日：2008-08-07

  Macrocyclic benzofused pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions are described herein.

  本文描述了大环苯并嘧啶化合物、包含这种化合物的组合物、制备这种化合物的方法，以及使用这种化合物和组合物治疗和预防疾病、病症和障碍的方法。