7-methylchroman-6-ol | 748151-96-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 7-methylchroman-6-ol
• 英文别名: 7-Methyl-3,4-dihydro-2H-1-benzopyran-6-ol；7-methyl-3,4-dihydro-2H-chromen-6-ol
• CAS: 748151-96-4
• 化学式: C₁₀H₁₂O₂
• 分子量: 164.204
• InChiKey: WKBOLUSEPYTMJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  7-methyl-1-oxaspiro[4.5]deca-6,9-dien-8-one 在 三氟化硼乙醚 作用下， 以 二氯甲烷 为溶剂， 反应 1.5h， 以62%的产率得到7-methylchroman-6-ol
  参考文献：
  名称：

  Plant-growth inhibitory activity of heliannuol derivatives

  摘要：

  In addition to (+)-, (-)- and (+/-)-heliannuol E, growth-inhibitory activities of five synthetic chromans and four tetrahydrobenzo[b]oxepins were examined against oat and cress. All heliannuol E isomers exhibited similar biological activities against cress, whereas when tested against oat roots, the unnatural optical isomer (+) showed no inhibitory activity. Four brominated chromans and two tetrahydrobenzo[b]oxepin derivatives also showed apparent inhibition against both cress and oat. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.phytochem.2004.03.035

文献信息

• Plant-growth inhibitory activity of heliannuol derivatives
  作者：Fuminao Doi、Taiga Ohara、Takahisa Ogamino、Takeshi Sugai、Keiko Higashinakasu、Kosumi Yamada、Hideyuki Shigemori、Koji Hasegawa、Shigeru Nishiyama

  DOI：10.1016/j.phytochem.2004.03.035

  日期：2004.5

  In addition to (+)-, (-)- and (+/-)-heliannuol E, growth-inhibitory activities of five synthetic chromans and four tetrahydrobenzo[b]oxepins were examined against oat and cress. All heliannuol E isomers exhibited similar biological activities against cress, whereas when tested against oat roots, the unnatural optical isomer (+) showed no inhibitory activity. Four brominated chromans and two tetrahydrobenzo[b]oxepin derivatives also showed apparent inhibition against both cress and oat. (C) 2004 Elsevier Ltd. All rights reserved.