(6aR,10aR)-1-Hydroxy-6,6,9-trimethyl-3-propyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene-2-carboxylic acid | 63953-77-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: (6aR,10aR)-1-Hydroxy-6,6,9-trimethyl-3-propyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene-2-carboxylic acid
• 英文别名: 6H-Dibenzo[b,d]pyran-2-carboxylicacid, 6a,7,10,10a-tetrahydro-1-hydroxy-6,6,9-trimethyl-3-propyl-, (6aR,10aR)-；(6aR,10aR)-1-hydroxy-6,6,9-trimethyl-3-propyl-6a,7,10,10a-tetrahydrobenzo[c]chromene-2-carboxylic acid
• CAS: 63953-77-5
• 化学式: C₂₀H₂₆O₄
• 分子量: 330.424
• InChiKey: NIVFVXYHFPSETN-ZIAGYGMSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• WATER-SOLUBLE FORMULATIONS, METHODS OF MAKING AND USE
  申请人：CANOPY GROWTH CORPORATION

  公开号：US20210177013A1

  公开（公告）日：2021-06-17

  Water-soluble formulations including cannabinoids or a cannabis -derived compound for use in beverages and foods, methods of preparing the formulations, and methods of preparing beverages and foods including the formulations are disclosed herein. In some embodiments, the water-soluble formulations comprise a cannabinoid or a cannabis -derived compound; an emulsifier comprising Quillaja saponins; a carrier oil, and a glycerin-based carrier surfactant.
• [EN] DEVICE AND METHOD FOR ADMINISTERING AN ACTIVE INGREDIENT<br/>[FR] DISPOSITIF ET PROCÉDÉ D'ADMINISTRATION DE PRINCIPES ACTIFS
  申请人：CANOPY GROWTH CORP

  公开号：WO2019171170A1

  公开（公告）日：2019-09-12

  This disclosure pertains to devices and methods for administering one or more active ingredients, e.g., cannabinoids, terpenes, etc. In particular, the devices and methods disclosed herein administer one or more cannabinoids in a mist for transmucosal and transdermal absorption. In one embodiment, the device contains compositions comprising purified active ingredients (e.g., cannabinoids, terpenes, etc.) and/or unique combinations thereof for delivery via a mist for transmucosal and transdermal adsorption. In one embodiment, the device contains two separate compositions in separate chambers, wherein each composition comprises one or more of the active ingredients. In one embodiment, a composition in one chamber comprises a purified cannabinoid and the composition in the other chamber comprises a purified terpene. In an embodiment, the device operates without heating the active ingredients.
• [EN] STABLE FORMULATIONS OF DRONABINOL<br/>[FR] FORMULATIONS STABLES DE DRONABINOL
  申请人：TRYAGX LABS INC

  公开号：WO2021163023A1

  公开（公告）日：2021-08-19

  Described herein are formulations, methods of manufacturing, and methods of treatment using formulations of cannabinoids that are stable at room temperature for at least about one to two years. In one embodiment, the composition is an oxidatively stable formulation of dronabinol.