2-Methoxy-N,N-dimethylnaphthalen-1-amine | 183890-19-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-Methoxy-N,N-dimethylnaphthalen-1-amine
• 英文别名: 2-methoxy-N,N-dimethylnaphthalen-1-amine
• CAS: 183890-19-9
• 化学式: C₁₃H₁₅NO
• 分子量: 201.26
• InChiKey: QDNOXGNJZLYWPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• METHODS OF REGULATING CANNABINOID RECEPTOR ACTIVITY-RELATED DISORDERS AND DISEASES
  申请人：The United States of America as represented by the Secretary, Department of Health and Human Service

  公开号：US20210038540A1

  公开（公告）日：2021-02-11

  This disclosure concerns the discovery of the use of fenoterol analogues for regulating cannabinoid (CB) receptor activity-related disorders and disease, such as dysregulated CB receptors, including treating a disorder or disease, such as a glioblastoma, hepatocellular carcinoma, liver cancer, colon cancer, and/or lung cancer, which is associated with altered cannabinoid receptor activity. In one example, the method includes administering to a subject having or at risk of developing a disorder or disease regulated by CB receptor activity an effective amount of a fenoterol analogue to reduce one or more symptoms associated with the disorder or disease regulated by CB receptor activity.