3-氨基呋喃并[2,3-b]吡啶-2-羧酸异戊酯 | 371943-09-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃
• 中文名称: 3-氨基呋喃并[2,3-b]吡啶-2-羧酸异戊酯
• 英文名称: Isopentyl 3-aminofuro[2,3-b]pyridine-2-carboxylate
• 英文别名: 3-methylbutyl 3-aminofuro[2,3-b]pyridine-2-carboxylate
• CAS: 371943-09-8
• 化学式: C₁₃H₁₆N₂O₃
• 分子量: 248.28
• InChiKey: LNYKBUVXEPFGNO-UHFFFAOYSA-N

物化性质

• 沸点：
  372.4±37.0 °C(Predicted)
• 密度：
  1.204±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  78.4
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• CONDENSED HETEROARYL DERIVATIVES
  申请人：Astellas Pharma Inc.

  公开号：EP1277738B1

  公开（公告）日：2011-03-30
• Fused heteroaryl derivatives
  申请人：Hayakawa Masahiko

  公开号：US20070037805A1

  公开（公告）日：2007-02-15

  The present invention provides a pharmaceutical composition which is useful as a phosphatidylinositol 3 kinase (PI3K) inhibitor and an antitumor agent, and it provides a novel bicyclic or tricyclic fused heteroaryl derivative or a salt thereof which possesses an excellent PI3K inhibiting activity and cancer cell growth inhibiting activity.
• FUSED HETEROARYL DERIVATIVES
  申请人：HAYAKAWA Masahiko

  公开号：US20100137584A1

  公开（公告）日：2010-06-03

  The present invention provides a pharmaceutical composition which is useful as a phosphatidylinositol 3 kinase (PI3K) inhibitor and an antitumor agent, and it provides a novel bicyclic or tricyclic fused heteroaryl derivative or a salt thereof which possesses an excellent PI3K inhibiting activity and cancer cell growth inhibiting activity.
• US7173029B2
  申请人：——

  公开号：US7173029B2

  公开（公告）日：2007-02-06
• US8067586B2
  申请人：——

  公开号：US8067586B2

  公开（公告）日：2011-11-29