1H-Indazole, 5-chloro-1-methyl-3-(4-piperidinyl)- | 742076-27-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡唑类
• 英文名称: 1H-Indazole, 5-chloro-1-methyl-3-(4-piperidinyl)-
• 英文别名: 5-chloro-1-methyl-3-piperidin-4-ylindazole
• CAS: 742076-27-3
• 化学式: C₁₃H₁₆ClN₃
• 分子量: 249.74
• InChiKey: YZJYFLJMWSAZPF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  29.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• THERAPEUTIC COMPOUNDS
  申请人：Gilead Sciences, Inc.

  公开号：US20180118734A1

  公开（公告）日：2018-05-03

  Compounds disclosed herein including compounds of Formula I: and salts thereof are provided. Pharmaceutical compositions comprising compounds disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection using compounds disclosed herein are also provided.

  本文披露的化合物包括式I的化合物及其盐。还提供了包括本文披露的化合物的药物组合物，用于制备本文披露的化合物的方法，用于制备本文披露的化合物的有用中间体，以及使用本文披露的化合物治疗HIV感染的治疗方法。
• Therapeutic compounds
  申请人：Gilead Sciences, Inc.

  公开号：US10800772B2

  公开（公告）日：2020-10-13

  Compounds disclosed herein including compounds of Formula I: and salts thereof are provided. Pharmaceutical compositions comprising compounds disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection using compounds disclosed herein are also provided.

  本文公开的化合物包括式 I 的化合物： 及其盐类。此外，还提供了包含本文所公开化合物的药物组合物、制备本文所公开化合物的工艺、用于制备本文所公开化合物的中间体以及使用本文所公开化合物治疗 HIV 感染的治疗方法。
• [EN] BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING HIV INFECTION<br/>[FR] DÉRIVÉS D'ACIDE BENZOTHIAZOL-6-YL-ACÉTIQUE ET LEUR UTILISATION POUR LE TRAITEMENT D'UNE INFECTION PAR LE VIH
  申请人：GILEAD SCIENCES INC

  公开号：WO2018064080A1

  公开（公告）日：2018-04-05

  Compounds disclosed herein including compounds of Formula I: and salts thereof are provided. Pharmaceutical compositions comprising compounds disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection using compounds disclosed herein are also provided.