| 885335-64-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 四环素类
• CAS: 885335-64-8
• 化学式: C₂₇H₂₉N₃O₇S
• 分子量: 539.609
• InChiKey: JHJWAAYSFBHSBT-SFFUMHGDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.92
• 重原子数：
  38.0
• 可旋转键数：
  4.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  164.63
• 氢给体数：
  5.0
• 氢受体数：
  10.0

文献信息

• TETRACYCLINE COMPOUNDS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS AND RELATED METHODS OF TREATMENT
  申请人：Abato Paul

  公开号：US20100190755A1

  公开（公告）日：2010-07-29

  The present invention pertains, at least in part, to substituted tetracycline compounds. The present invention also pertains to methods for treating rheumatoid arthritis in a subject, comprising administering to the subject a tetracycline compound of the invention.

  本发明至少部分涉及替代四环素化合物。本发明还涉及治疗类风湿性关节炎的方法，包括向患者投与本发明的四环素化合物。
• SUBSTITUTED TETRACYCLINE COMPOUNDS
  申请人：Abato Paul

  公开号：US20140155357A1

  公开（公告）日：2014-06-05

  The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
• US8466132B2
  申请人：——

  公开号：US8466132B2

  公开（公告）日：2013-06-18