2-(3-methoxyphenylamino)-3-(4-methylpiperazin-1-yl)-1,4-dihydronaphthalene-1,4-dione | 892230-32-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(3-methoxyphenylamino)-3-(4-methylpiperazin-1-yl)-1,4-dihydronaphthalene-1,4-dione
• 英文别名: 2-[(3-Methoxyphenyl)amino]-3-(4-methylpiperazin-1-YL)-1,4-dihydronaphthalene-1,4-dione；2-(3-methoxyanilino)-3-(4-methylpiperazin-1-yl)naphthalene-1,4-dione
• CAS: 892230-32-9
• 化学式: C₂₂H₂₃N₃O₃
• mdl: MFCD14712384
• 分子量: 377.443
• InChiKey: BRYNBEMCVAOKCU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  61.9
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-(3-methoxyphenylamino)-3-(4-methylpiperazin-1-yl)-1,4-dihydronaphthalene-1,4-dione 、 碘甲烷 在 三乙胺 作用下， 以 乙醇 为溶剂， 反应 120.0h， 以77%的产率得到4-[3-(3-methoxyphenylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl]-1,1-dimethylpiperazinium iodide
  参考文献：
  名称：

  Synthesis of photoactive 1-methyl-1-R-4-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)piperazinium salts

  摘要：

  Photoactive 4-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)piperazinium salts were synthesized by alkylation of 3-chloro-2-(piperazin-1-yl)-and 2-arylamino-3-(4-methylpiperazin-1-yl)-1,4-naphthoquinones. Light sensitivities of materials obtained by adsorption of the synthesized piperazinium salts from solution onto oxidized aluminum support were estimated.

  DOI：

  10.1134/s1070428011120086
• 作为产物：
  描述：

  N-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-(3-methoxyphenyl)acetamide 在 potassium hydroxide 作用下， 以 1,4-二氧六环 、 甲醇 、 乙醇 为溶剂， 反应 30.0h， 生成 2-(3-methoxyphenylamino)-3-(4-methylpiperazin-1-yl)-1,4-dihydronaphthalene-1,4-dione
  参考文献：
  名称：

  Synthesis of photoactive 1-methyl-1-R-4-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)piperazinium salts

  摘要：

  Photoactive 4-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)piperazinium salts were synthesized by alkylation of 3-chloro-2-(piperazin-1-yl)-and 2-arylamino-3-(4-methylpiperazin-1-yl)-1,4-naphthoquinones. Light sensitivities of materials obtained by adsorption of the synthesized piperazinium salts from solution onto oxidized aluminum support were estimated.

  DOI：

  10.1134/s1070428011120086

文献信息

• Synthesis of photoactive 1-methyl-1-R-4-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)piperazinium salts
  作者：V. N. Berezhnaya、V. V. Shelkovnikov、S. V. Korotaev

  DOI：10.1134/s1070428011120086

  日期：2011.12

  Photoactive 4-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)piperazinium salts were synthesized by alkylation of 3-chloro-2-(piperazin-1-yl)-and 2-arylamino-3-(4-methylpiperazin-1-yl)-1,4-naphthoquinones. Light sensitivities of materials obtained by adsorption of the synthesized piperazinium salts from solution onto oxidized aluminum support were estimated.