1-iodo-4-triethylsiloxybutane | 250715-63-0

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 1-iodo-4-triethylsiloxybutane
• 英文别名: Triethyl(4-iodobutoxy)silane
• CAS: 250715-63-0
• 化学式: C₁₀H₂₃IOSi
• 分子量: 314.282
• InChiKey: BLBDKYBWGMBURU-UHFFFAOYSA-N

物化性质

• 沸点：
  261.9±23.0 °C(Predicted)
• 密度：
  1.234±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.22
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  5-羟基-1,10-菲咯啉 、 1-iodo-4-triethylsiloxybutane 在 sodium hydroxide 作用下， 以 二甲基亚砜 为溶剂， 反应 14.6h， 生成
  参考文献：
  名称：

  Synthesis of Readily Cleavable Immobilized 1,10-Phenanthroline Resins

  摘要：

  1,10-Phenanthroline is derivatized and ultimately immobilized on two different polystyrene/divinylbenzene solid supports using convenient methodology. All syntheses are amenable to semiautomatic processing and are scalable for high-throughput screening. A domino copper-catalyzed coupling-cyclization reaction is used to illustrate applicability in catalytic studies.

  DOI：

  10.1021/ol049101i
• 作为产物：
  描述：

  呋喃 、 三乙基硅烷 在 palladium dichloride 碘甲烷 作用下， 反应 5.0h， 以70%的产率得到1-iodo-4-triethylsiloxybutane
  参考文献：
  名称：

  Selective synthesis of halosilanes from hydrosilanes and utilization for organic synthesis

  摘要：

  Selective synthesis of halosilanes has been examined. Various types of halosilanes and halohydrosilanes, such as R3SiX, R2SiHX, R2SiX2, RSiH2X, RSiHX2 (X = Cl, Br, F), were obtained by the reactions of the corresponding hydrosilanes with Cu(II)-based reagents selectively in high yields. This method could be also applied to the synthesis of chlorofluorosilanes and chlorohydrogermanes. On the other hand, iodo- and bromosilanes and germanes were obtained by Pd- or Ni-catalyzed hydride-halogen exchange reactions of hydrosilanes with alkyl or allyl halides. Their synthetic applications have been demonstrated by using iodo-and bromosilanes and chlorofluorosilanes. (C) 2003 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(03)00254-7

文献信息

• Ring-Opening Iodo- and Bromosilation of Cyclic Ethers by Treatment with Iodo- and Bromotrialkylsilane Equivalents
  作者：Joji Ohshita、Arihiro Iwata、Fujio Kanetani、Atsutaka Kunai、Yasushi Yamamoto、Chinami Matui

  DOI：10.1021/jo990722c

  日期：1999.10.1