1,2,5-trihydroxynaphthalene | 24281-29-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,2,5-trihydroxynaphthalene
• 英文别名: Naphthalene-1,2,5-triol
• CAS: 24281-29-6
• 化学式: C₁₀H₈O₃
• 分子量: 176.172
• InChiKey: QKCAWPZWWHAZBB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• Ultra-Sensitive Chemiluminescent Substrates for Enzymes and Their Conjugates
  申请人：Giri Pal Brij

  公开号：US20070225498A1

  公开（公告）日：2007-09-27

  New chemiluminescent compounds, stable in aqueous buffers, for use in biological assaying include acridanebased compounds and (1,2)-dioxetanes. Among the new acridanebased compounds are water-soluble acridanes, enhancer coupled acridanes, bis and trisacridanes as well as acridane-(1,2)-dioxetanes. Among the new (1,2)-dioxetanes are electron deficient group-containing dioxetanes and tethered bis-1,2-dioxetanes. The (1,2)-dioxetanes are useful as substrates for various enzymes. The acridanes can be admixed with an oxidizing agent. An aqueous buffer and, optionally, a stabilizer to form a substrate or reagent formulation useful for assaying, inter alia, HRP.

  新的化学发光化合物，稳定在水性缓冲液中，用于生物分析包括基于吖啶的化合物和(1,2)-二氧杂环辛烷。在新的基于吖啶的化合物中包括水溶性吖啶、增强剂偶联的吖啶、双吖啶和三吖啶以及吖啶-(1,2)-二氧杂环辛烷。在新的(1,2)-二氧杂环辛烷中包括含电子亏损基团的二氧杂环辛烷和连接的双-1,2-二氧杂环辛烷。这些(1,2)-二氧杂环辛烷可作为各种酶的底物。吖啶可以与氧化剂混合。水性缓冲液和可选的稳定剂可形成用于分析的底物或试剂配方，用于分析，包括HRP等。
• ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES
  申请人：Giri Brij Pal

  公开号：US20150031889A1

  公开（公告）日：2015-01-29

  New chemiluminescent compounds, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and 1,2-dioxetanes. Among the new acridane-based compounds are water-soluble acridanes, enhancer coupled acridanes, bis and tris-acridanes as well as acridane-1,2-dioxetanes. Among the new 1,2-dioxetanes are electron deficient group-containing dioxetanes and tethered bis-1,2-dioxetanes. The 1,2-dioxetanes are useful as substrates for various enzymes. The acridanes can be admixed with an oxidizing agent, an aqueous buffer and, optionally, a stabilizer to form a substrate or reagent formulation useful for assaying, inter alia, HRP.

  新的化学发光化合物，稳定在水溶液缓冲液中，用于生物测定，包括基于蒽醌的化合物和1,2-二氧杂环烷。新的基于蒽醌的化合物包括水溶性蒽醌，增强剂偶联蒽醌，双蒽醌和三蒽醌以及蒽醌-1,2-二氧杂环烷。新的1,2-二氧杂环烷包括含电子亏损基团的二氧杂环烷和连接的双1,2-二氧杂环烷。1,2-二氧杂环烷可用作各种酶的底物。蒽醌可以与氧化剂、水溶液缓冲液和必要时稳定剂混合，形成用于测定HRP等的底物或试剂配方。
• NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES
  申请人：Giri Brij Pal

  公开号：US20140073771A1

  公开（公告）日：2014-03-13

  New chemiluminescent compounds, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and 1,2-dioxetanes. Among the new acridane-based compounds are water-soluble acridanes, enhancer coupled acridanes, bis and tris-acridanes as well as acridane-1,2-dioxetanes. Among the new 1,2-dioxetanes are electron deficient group-containing dioxetanes and tethered bis-1,2-dioxetanes. The 1,2-dioxetanes are useful as substrates for various enzymes. The acridanes can be admixed with an oxidizing agent. an aqueous buffer and, optionally, a stabilizer to form a substrate or reagent formulation useful for assaying, inter alia, HRP.

  新的化学发光化合物，可以在水性缓冲液中稳定使用，用于生物测定，包括基于蒽醌的化合物和1,2-二氧杂环烷。其中，新的基于蒽醌的化合物包括水溶性蒽醌、增强剂偶联蒽醌、双蒽醌和三蒽醌以及蒽醌-1,2-二氧杂环烷。新的1,2-二氧杂环烷包括含电子亏损基团的二氧杂环烷和连接的双1,2-二氧杂环烷。1,2-二氧杂环烷可用作各种酶的底物。蒽醌可以与氧化剂、水性缓冲液以及可选的稳定剂混合，形成用于测定HRP等的底物或试剂配方。
• Process for producing a liquid crystalline polyester of a cyclohexanedicarboxylic acid and an aromatic diol
  申请人：Chisso Corporation

  公开号：EP0286444A2

  公开（公告）日：1988-10-12

  A process for producing liquid crystalline polymers from cyclohexanedicarboxylic acids and aromatic diols comprise polycondensing the acids and diols, optionally together with a hydroxycarboxylic acid, using a combination of thionyl chloride and pyridine as a condensing agent.

  一种利用环己烷二羧酸和芳香族二元醇生产液晶聚合物的工艺，包括利用亚硫酰氯和吡啶的组合作为缩合剂，将环己烷二羧酸和芳香族二元醇（可选择与羟基羧酸一起）进行缩合。
• Polyester and process for producing the same
  申请人：MITSUBISHI KASEI CORPORATION

  公开号：EP0404116A2

  公开（公告）日：1990-12-27

  This invention provides a polyester, which is composed of a constitutive unit of formula (I) and a constitutive unit of formula (II) in a proportion of (I)/(II) of being from 0.1/99.9 to 99.1/0.1 as a molar ratio and which has a logarithmic viscosity (ηinh) of being 0.1 or more: where R₀ is a fluorine-free monovalent organic group having from 1 to 40 carbon atoms, R₁, R₂ and R₃ are independently a divalent organic group having from 1 to 40 carbon atoms, and n is 0 or 1. This invention also provides a method of preparing the polyester, in which (A) a monoepoxy compound of formula (III) where R₀ and n have the same meanings as mentioned above, (B) a polyester or a polyester precursor and (C) a dicarboxylic acid compound are reacted and polymerized.

  本发明提供了一种聚酯，它由式(I)的组成单元和式(II)的组成单元组成，摩尔比(I)/(II)为 0.1/99.9 至 99.1/0.1，对数粘度(ηinh)为 0.1 或以上： 其中 R₀ 是具有 1 至 40 个碳原子的无氟一价有机基团，R₁、R₂ 和 R₃ 独立地是具有 1 至 40 个碳原子的二价有机基团，n 是 0 或 1。 本发明还提供了一种制备聚酯的方法，其中 (A) 式 (III) 的单环氧化合物 其中 R₀ 和 n 的含义与上述相同，(B) 一种聚酯或一种聚酯前体和 (C) 一种二羧酸化合物反应并聚合。