[3-Butyl-1,1-dioxo-1,3-dihydro-1λ⁶-benzothiazol-(2Z)-ylidene]-acetic acid | 610316-15-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻二嗪
• 英文名称: [3-Butyl-1,1-dioxo-1,3-dihydro-1λ⁶-benzothiazol-(2Z)-ylidene]-acetic acid
• CAS: 610316-15-9
• 化学式: C₁₃H₁₅NO₄S
• 分子量: 281.332
• InChiKey: WUEGSCXLJVEIHD-XFXZXTDPSA-N

反应信息

• 作为反应物：
  描述：

  [3-Butyl-1,1-dioxo-1,3-dihydro-1λ⁶-benzothiazol-(2Z)-ylidene]-acetic acid 在 三乙胺 盐酸羟胺 、 1-羟基苯并三唑 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以73%的产率得到2-[3-Butyl-1,1-dioxo-1,3-dihydro-1λ⁶-benzothiazol-(2Z)-ylidene]-N-hydroxy-acetamide
  参考文献：
  名称：

  Synthesis and PDF inhibitory activities of novel benzothiazolylidenehydroxamic acid derivatives

  摘要：

  A novel series of benzothiazolylidenehydroxamic acid derivatives has been designed and synthesized as PDF inhibitors. Some of this novel class of PDF inhibitors exhibited micromolar order enzyme inhibitory activity and antibacterial activity. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(03)00675-9
• 作为产物：
  描述：

  [3-Butyl-1,1-dioxo-1,3-dihydro-1λ⁶-benzothiazol-(2Z)-ylidene]-acetic acid ethyl ester 在 氢氧化钾 作用下， 以 乙醇 为溶剂， 反应 5.0h， 以89%的产率得到[3-Butyl-1,1-dioxo-1,3-dihydro-1λ⁶-benzothiazol-(2Z)-ylidene]-acetic acid
  参考文献：
  名称：

  Synthesis and PDF inhibitory activities of novel benzothiazolylidenehydroxamic acid derivatives

  摘要：

  A novel series of benzothiazolylidenehydroxamic acid derivatives has been designed and synthesized as PDF inhibitors. Some of this novel class of PDF inhibitors exhibited micromolar order enzyme inhibitory activity and antibacterial activity. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(03)00675-9