1-(5-dimethylaminonaphthalene-1-sulfonyl)-N-phenylpyrrolidine-2-carboxamide | 1259528-81-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-(5-dimethylaminonaphthalene-1-sulfonyl)-N-phenylpyrrolidine-2-carboxamide
• 英文别名: 1-(5-(dimethylamino)naphthalen-1-ylsulfonyl)-N phenylpyrrolidine-2-carboxamide；1-[5-(dimethylamino)naphthalen-1-yl]sulfonyl-N-phenylpyrrolidine-2-carboxamide
• CAS: 1259528-81-8
• 化学式: C₂₃H₂₅N₃O₃S
• 分子量: 423.536
• InChiKey: SYKGAELKXRGWEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  78.1
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY
  申请人：Castells Boliart Josep

  公开号：US20120142936A1

  公开（公告）日：2012-06-07

  Novel compounds are continually sought after to treat and prevent diseases and disorders. The invention relates to 1-(sulfonyl)-N-phenylpyrrolidine-2-carboxamides which are useful for being biologically and pharmacologically screened, and to contribute to the exploration and identification of new lead molecules that are capable of modulating the functional activity of a biological target.

  小说化合物不断被寻求用于治疗和预防疾病和紊乱。该发明涉及对1-(磺酰基)-N-苯基吡咯烷-2-羧酰胺的利用，这些化合物有助于进行生物学和药理学筛选，并有助于探索和鉴定能够调节生物靶标功能活性的新引物分子。
• LIBRARIES OF 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES FOR DRUG DISCOVERY
  申请人：CASTELLS BOLIART JOSEP

  公开号：US20120122950A1

  公开（公告）日：2012-05-17

  New compounds are continually being sought for the treatment and prevention of disorders. The invention relates to 1-(sulfonyl)-N-phenyl-pyrrolidine 2-carboxamides which can be used in the search for, and identification of, new lead compounds that could modulate the functional activity of a biological target.

  新化合物不断被寻求用于治疗和预防疾病。本发明涉及1-(磺酰基)-N-苯基-吡咯烷-2-羧酰胺，可用于寻找和识别可能调节生物靶标功能活性的新引物化合物。
• LIBRARIES OF 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY
  申请人：CASTELLS BOLIART JOSEP

  公开号：US20120122709A1

  公开（公告）日：2012-05-17

  New compounds are continually sought after for the treatment and prevention of disorders. The invention relates to 1-(sulfonyl)-N-phenylpyrrolidine-2-carboxamides which can be biologically and pharmacologically traced, in order to be used in the search for, and identification of, new lead compounds that can modulate the functional activity of a biological target.

  不断寻求治疗和预防疾病的新化合物。本发明涉及1-(磺酰基)-N-苯基吡咯烷-2-羧酰胺，可在生物学和药理学上追踪，以便用于寻找和识别可以调节生物靶点的功能活性的新引导化合物。
• N-PHENYL-1-SULFONYL-2-PYRROLIDINE CARBOXAMIDE LIBRARIES FOR DRUG DISCOVERY
  申请人：Institut Univ. de Ciència i Tecnologia, S.A.

  公开号：EP2447249A1

  公开（公告）日：2012-05-02

  New compounds are continually being sought for the treatment and prevention of disorders. The invention relates to 1-(sulfonyl)-N-phenyl-pyrrolidine 2-carboxamides which can be used in the search for, and identification of, new lead compounds that could modulate the functional activity of a biological target.

  人们一直在寻找新的化合物来治疗和预防疾病。本发明涉及 1-(磺酰基)-N-苯基吡咯烷 2-甲酰胺，可用于寻找和鉴定可调节生物靶标功能活性的新先导化合物。
• N-PHENYL-1-SULFONYL-2-PYRROLIDINE CARBOXAMIDES LIBRARIES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY
  申请人：Institut Univ. de Ciència i Tecnologia, S.A.

  公开号：EP2452934A1

  公开（公告）日：2012-05-16

  New compounds are continually sought after for the treatment and prevention of disorders. The invention relates to 1-(sulfonyl)-N-phenylpyrrolidine-2-carboxamides which can be biologically and pharmacologically traced, in order to be used in the search for, and identification of, new lead compounds that can modulate the functional activity of a biological target.

  人们一直在寻找新的化合物来治疗和预防疾病。本发明涉及 1-(磺酰基)-N-苯基吡咯烷-2-羧酰胺，可对其进行生物学和药理学追踪，以用于寻找和鉴定可调节生物靶标功能活性的新先导化合物。