3,3-dimethyl-3,4-dihydro-2H-benzo[g]chromen-2-ol | 1280733-19-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并吡喃类
• 英文名称: 3,3-dimethyl-3,4-dihydro-2H-benzo[g]chromen-2-ol
• 英文别名: 3,3-Dimethyl-2,4-dihydrobenzo[g]chromen-2-ol
• CAS: 1280733-19-8
• 化学式: C₁₅H₁₆O₂
• 分子量: 228.291
• InChiKey: CSYGEXVPWLFZKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• METHODS FOR LABELING A SUBSTRATE USING A HETERO-DIELS-ALDER REACTION
  申请人：POPIK VLADIMIR V.

  公开号：US20110108411A1

  公开（公告）日：2011-05-12

  Methods for labeling a substrate using a hetero-Diels-Alder reaction are disclosed. The hetero-Diels-Alder reaction includes the reaction of an o-quinone methide (e.g., an o-naphthoquinone methide) with a polarized olefin to form a hetero-Diels-Alder adduct. The o-quinone methide or the polarized olefin can be attached to a surface of a substrate, and the other of the o-quinone methide or the polarized olefin can include a detectable label. The o-quinone methide can conveniently be generated by irradiation of a precursor compound, preferably in an aqueous solution, suspension, or dispersion.

  公开了使用异构Diels-Alder反应标记基底的方法。异构Diels-Alder反应包括将邻苯二酚亚甲基（例如，邻萘醌亚甲基）与极化烯烃反应，形成异构Diels-Alder加合物。邻苯二酚亚甲基或极化烯烃可以附着在基底的表面上，另一个邻苯二酚亚甲基或极化烯烃可以包含可检测的标记。邻苯二酚亚甲基可以通过辐照前体化合物方便地生成，最好在水溶液、悬浮液或分散液中。
• Methods for Labeling a Substrate Using a Hetero-Diels-Alder Reaction
  申请人：Popik Vladimir V.

  公开号：US20110257047A1

  公开（公告）日：2011-10-20

  Methods for labeling a substrate using a hetero-Diels-Alder reaction are disclosed. The hetero-Diels-Alder reaction includes the reaction of an o-quinone methide (e.g., an o-naphthoquinone methide) with a polarized olefin to form a hetero-Diels-Alder adduct. The o-quinone methide or the polarized olefin can be attached to a surface of a substrate, and the other of the o-quinone methide or the polarized olefin can include a detectable label. The o-quinone methide can conveniently be generated by irradiation of a precursor compound, preferably in an aqueous solution, suspension, or dispersion.

  本发明揭示了使用杂Diels-Alder反应标记底物的方法。杂Diels-Alder反应包括o-醌甲烷（例如o-萘醌甲烷）与极性烯烃反应，形成杂Diels-Alder加合物。o-醌甲烷或极性烯烃可以附着在底物的表面上，而另一个o-醌甲烷或极性烯烃可以包含可检测的标签。o-醌甲烷可以方便地通过辐照前体化合物（最好是在水溶液、悬浮液或分散液中）产生。
• US9090542B2
  申请人：——

  公开号：US9090542B2

  公开（公告）日：2015-07-28