| 835884-52-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 四环素类
• CAS: 835884-52-1
• 化学式: C₂₆H₃₁N₃O₉
• 分子量: 529.547
• InChiKey: GICWBAOLCHGIJA-INJPKEBHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.46
• 重原子数：
  38.0
• 可旋转键数：
  8.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  199.72
• 氢给体数：
  6.0
• 氢受体数：
  11.0

文献信息

• Methods for Treating Spinal Muscular Atrophy Using Tetracycline Compounds
  申请人：Berniac Joel

  公开号：US20090118269A1

  公开（公告）日：2009-05-07

  Methods for using tetracycline compounds for the treatment of spinal muscular atrophy are described.
• Substituted Tetracycline Compounds
  申请人：Berniac Joel

  公开号：US20100022483A1

  公开（公告）日：2010-01-28

  The present invention pertains, at least in part, to methods of treating a microorganism-associated infection in a subject comprising administering to said subject an effective amount of a tetracycline compound.
• SUBSTITUTED TETRACYCLINE COMPOUNDS
  申请人：Paratek Pharmaceuticals, Inc.

  公开号：US20150045329A1

  公开（公告）日：2015-02-12

  The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
• US7935687B2
  申请人：——

  公开号：US7935687B2

  公开（公告）日：2011-05-03
• US8399437B2
  申请人：——

  公开号：US8399437B2

  公开（公告）日：2013-03-19