1,1-dimethyl-2-((E)-oct-2-en-7-yn-1-ylidene)hydrazine | 1226885-69-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,1-dimethyl-2-((E)-oct-2-en-7-yn-1-ylidene)hydrazine
• CAS: 1226885-69-3
• 化学式: C₁₀H₁₆N₂
• 分子量: 164.25
• InChiKey: CKQGJSMVNREKIT-XWQZHWJLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.89
• 重原子数：
  12.0
• 可旋转键数：
  5.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  15.6
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  正丁基锂 、 1,1-dimethyl-2-((E)-oct-2-en-7-yn-1-ylidene)hydrazine 以 乙醚 为溶剂， 以94%的产率得到2-[(E)-dodec-6-en-11-yn-5-yl]-1,1-dimethylhydrazine
  参考文献：
  名称：

  Novel Radical Cyclization Method Accompanied by Elimination of Hydrazyl Radical

  摘要：

  The potential of hydrazine group as the new radical leaving group was studied. Radical cyclization of (E)-1,1-dialkyl-2-(1-alkyloct-2-en-7-ynyl)hydrazines with n-Bu(3)SnH/AIBN, followed by protodestannylation, gave 1-alkenyl-2-methylenecyclopentanes, which arose by 5-exo cyclization and subsequent beta-elimination of hydrazyl radical.

  DOI：

  10.3987/com-09-s(s)115
• 作为产物：
  描述：

  (2E)-2-octen-7-ynal 、 偏二甲肼 以 甲苯 为溶剂， 以91%的产率得到1,1-dimethyl-2-((E)-oct-2-en-7-yn-1-ylidene)hydrazine
  参考文献：
  名称：

  Novel Radical Cyclization Method Accompanied by Elimination of Hydrazyl Radical

  摘要：

  The potential of hydrazine group as the new radical leaving group was studied. Radical cyclization of (E)-1,1-dialkyl-2-(1-alkyloct-2-en-7-ynyl)hydrazines with n-Bu(3)SnH/AIBN, followed by protodestannylation, gave 1-alkenyl-2-methylenecyclopentanes, which arose by 5-exo cyclization and subsequent beta-elimination of hydrazyl radical.

  DOI：

  10.3987/com-09-s(s)115