N~3~,N~3~,N~6~,N~6~-Tetramethyl-9-(pentafluorophenyl)-9H-xanthene-3,6-diamine | 296277-09-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: N~3~,N~3~,N~6~,N~6~-Tetramethyl-9-(pentafluorophenyl)-9H-xanthene-3,6-diamine
• 英文别名: 3-N,3-N,6-N,6-N-tetramethyl-9-(2,3,4,5,6-pentafluorophenyl)-9H-xanthene-3,6-diamine
• CAS: 296277-09-3
• 化学式: C₂₃H₁₉F₅N₂O
• 分子量: 434.4
• InChiKey: PJVIQSJYKHKPNN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  31
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  15.7
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• Method of Selecting a Cardiomyoctye Using Intracellular Mitochondria as an Indicator
  申请人：Hattori Fumiyuki

  公开号：US20080090266A1

  公开（公告）日：2008-04-17

  The invention relates to methods of selecting a cardiomyocyte from a cell population derived from a whole heart or a differentiated cell population derived from a stem cell without genetic alteration. Specifically, the invention relates to a method of selecting a cardiomyocyte from a cardiomyocyte-containing cell mixture without genetic alteration of a cardiomyocyte, on the basis of a relative content of cellular mitochondria and/or a relative mitochondrial transmembrane potential of the cell. The invention also relates to methods of enriching a cardiomyocyte from a cardiomyocyte-containing cell mixture without genetic alteration of a cardiomyocyte, producing a cardiomyocyte without genetic alteration of a cardiomyocyte, and evaluating the ratio of a cardiomyocyte in a cardiomyocyte-containing cell mixture.
• METHODS FOR QUANTIFYING FRATAXIN ACTIVITY
  申请人：Larimar Therapeutics, Inc.

  公开号：US20210156874A1

  公开（公告）日：2021-05-27

  The present disclosure provides methods, compositions and kits for measuring activity of a frataxin (FXN) protein, e.g., an FXN fusion protein. The present invention also provides methods for identifying compounds capable of modulating activity of an FXN protein, e.g., an FXN fusion protein.
• US8623649B2
  申请人：——

  公开号：US8623649B2

  公开（公告）日：2014-01-07