Phosphorous acid 2'-[bis-(3,5-dimethyl-phenoxy)-phosphanyloxy]-[1,1']binaphthalenyl-2-yl ester bis-(3,5-dimethyl-phenyl) ester | 142940-74-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Phosphorous acid 2'-[bis-(3,5-dimethyl-phenoxy)-phosphanyloxy]-[1,1']binaphthalenyl-2-yl ester bis-(3,5-dimethyl-phenyl) ester
• CAS: 142940-74-7
• 化学式: C₅₂H₄₈O₆P₂
• 分子量: 830.897
• InChiKey: YGWAGYZEMJGVEG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  15.65
• 重原子数：
  60.0
• 可旋转键数：
  13.0
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  55.38
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  S-1,1'-联-2-萘酚 、 Phosphorochloridous acid bis-(3,5-dimethyl-phenyl) ester 在 三乙胺 作用下， 以 甲苯 为溶剂， 以64%的产率得到Phosphorous acid 2'-[bis-(3,5-dimethyl-phenoxy)-phosphanyloxy]-[1,1']binaphthalenyl-2-yl ester bis-(3,5-dimethyl-phenyl) ester
  参考文献：
  名称：

  Asymmetric hydroformylation of vinyl acetate by use of chiral bis(triarylphosphite)-rhodium(I) complexes

  摘要：

  Bis(triarylphosphite) ligands 1 - 4 were prepared in optically pure forms from (R)- or (S)-binaphthol and (ArO)2PCl, and their Rh(I) complexes have been used as catalysts for hydroformylation of vinyl acetate. The corresponding branched aldehyde, 2-acetoxypropanal, was given in up to 95% regioselectivity and in 49% ee.

  DOI：

  10.1016/s0957-4166(00)82286-7