naphthalen-2-yl(p-tolyl)methanaminium chloride | 1067428-65-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: naphthalen-2-yl(p-tolyl)methanaminium chloride
• 英文别名: naphthalen-2-yl(p-tolyl)methanamine hydrochloride；(4-Methylphenyl)-naphthalen-2-ylmethanamine;hydrochloride
• CAS: 1067428-65-2
• 化学式: C₁₈H₁₇N*ClH
• 分子量: 283.801
• InChiKey: QCHIPCAUWKGVLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.62
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  26
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• METHODS OF PREPARING PRIMARY, SECONDARY AND TERTIARY CARBINAMINE COMPOUNDS IN THE PRESENCE OF AMMONIA
  申请人：Thadani Avinash N.

  公开号：US20100174090A1

  公开（公告）日：2010-07-08

  The present application relates to novel methods for the preparation of primary, secondary and tertiary carbinamine compounds, particularly the preparation of compounds of formulae I, IV and VI, from a carbonyl compound of formula II in the presence of ammonia or an ammonium equivalent of the formula NH 4 + X − , by way of allylation, crotylation, arylation, reductive amination and catalytic hydrogenation.
• METHODS OF PREPARING SECONDARY CARBINAMINE COMPOUNDS WITH BORONIC ACIDS
  申请人：Thadani Avinash N.

  公开号：US20100298572A1

  公开（公告）日：2010-11-25

  The present application relates to novel methods for the preparation of secondary carbinamine compounds, particularly the preparation of secondary carbinamine compounds of the formula Ia, formula Ib or formula IV from aldehydes of the formula II and boronic acids of the formula III or formula V, in the presence of ammonia or an ammonia equivalent of the formula NH 4+X− .
• US8350047B2
  申请人：——

  公开号：US8350047B2

  公开（公告）日：2013-01-08
• US8383859B2
  申请人：——

  公开号：US8383859B2

  公开（公告）日：2013-02-26
• [EN] METHODS OF PREPARING SECONDARY CARBINAMINE COMPOUNDS WITH BORONIC ACIDS<br/>[FR] PROCÉDÉS DE PRÉPARATION DE COMPOSÉS CARBINAMIDE SECONDAIRES AVEC DES ACIDES BORONIQUES
  申请人：KANATA CHEMICAL TECHNOLOGIES I

  公开号：WO2008119161A1

  公开（公告）日：2008-10-09

  [EN] The present application relates to novel methods for the preparation of secondary carbinamine compounds, particularly the preparation of secondary carbinamine compounds of the formula Ia, formula Ib or formula IV from aldehydes of the formula II and boronic acids of the formula III or formula V, in the presence of ammonia or an ammonia equivalent of the formula NH^4+X-.
  [FR] La présente invention concerne de nouveaux procédés de préparation de composés carbinamide secondaires, en particulier la préparation de composés carbinamide secondaires représentés par la formule la, la formule lb ou la formule IV à partir d'aldéhydes représentés par la formule II et des acides boroniques représentés pas la formule III ou V, en présence d'ammoniac ou d'un équivalent d'ammoniac représenté par la formule NH^4+X-.