The present invention provides for a method for detecting the presence of isocyanate in a sample by (a) contacting an isocyanate derivatizing agent with a sample under conditions suitable to the formation of a reaction product capable of detection and (b) detecting the presence or absence of the reaction product as an indication of the presence or absence of isocyanate in said sample. The present invention also provides a method of quantifying the total isocyanate presence by quantifying the reaction product An organic compound useful for detecting the total quantity of isocyanate in an environmental sample is disclosed. The compound is 1,8-diaminonaphthalene (DAN), a bifunctional nucleophilic derivatizing agent. Methods for detecting a particular isocyanate monomer or the total isocyanate in environmental samples using DAN and related isocyanate derivatizing agents are provided.
本发明提供了一种检测样品中
异氰酸酯存在的方法,包括(a)在适宜形成可检测的反应产物的条件下,将
异氰酸酯衍生化试剂与样品接触,以及(b)检测反应产物的存在或缺失,作为样品中
异氰酸酯存在或缺失的指示。本发明还提供了一种通过量化反应产物来量化总
异氰酸酯存在的方法。本发明还揭示了一种有机化合物,用于检测环境样品中
异氰酸酯的总量。该化合物为
1,8-二氨基萘(
DAN),一种双功能亲核
衍生化试剂。本发明提供了使用
DAN和相关
异氰酸酯衍生化试剂来检测特定
异氰酸酯单体或环境样品中总
异氰酸酯的方法。