6,6-Diethoxy-1,1,1,2,2,3,3,4,4-nonafluoro-hexane | 142502-78-1

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 英文名称: 6,6-Diethoxy-1,1,1,2,2,3,3,4,4-nonafluoro-hexane
• 英文别名: 6,6-diethoxy-1,1,1,2,2,3,3,4,4-nonafluorohexane
• CAS: 142502-78-1
• 化学式: C₁₀H₁₃F₉O₂
• 分子量: 336.198
• InChiKey: GCQVBZRJTYKMLH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.24
• 重原子数：
  21.0
• 可旋转键数：
  8.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.46
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  乙醇 、 1-acetoxy-2-(nonafluorobutyl)-1-iodoethane 反应 5.0h， 以95%的产率得到6,6-Diethoxy-1,1,1,2,2,3,3,4,4-nonafluoro-hexane
  参考文献：
  名称：

  Synthése de fluoroalkyl éthanl : RFCH2CHO

  摘要：

  Aldehydes RFCH2CHO (R(F) is a linear perfluoroalkyl chain) have been obtained in the addition reaction of R(F)I to vinyl acetate in the presence of zinc. RFCH2CHIOAc is formed as an intermediate in the course of the reaction. Under appropriate conditions, RFCH2CHO and its acylal or acetal derivatives are obtained in good yields.

  DOI：

  10.1016/s0040-4039(00)92222-6

文献信息

• Synthesis of 2-perfluoroalkyl-substituted acetals from the one-pot reaction of perfluoroalkyl iodides with vinyl ether and alcoholates
  作者：Shizheng Zhu、Chaoyue Qing、Chenming Zhou、Jie Zhang、Bin Xu

  DOI：10.1016/0022-1139(96)03468-9

  日期：1996.7

  Treatment of perfluoroalkyl iodides, RfI (Rf=C4F9, ClC4F8), with alcoholales and vinyl ethyl ether gave 2-perfluoroalkyl acetals via perfluoroalkyl radical intermediates. Both Rf and RfCH2CHOEt radicals were detected by ESR spectroscopy. A single-electron-transfer mechanism is proposed for this reaction.

  用醇醛和乙烯基乙基醚处理全氟烷基碘化物R f I（R f＝ C 4 F 9，ClC 4 F 8），通过全氟烷基自由基中间体得到2-全氟烷基乙缩醛。通过ESR光谱法检测到R f和R f CH 2 CHOEt自由基。提出了用于该反应的单电子转移机理。