4-(1-Hydroxy-2-phenyl-ethyl)-6-iodo-3-methyl-1H-pyridin-2-one | 356056-44-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 4-(1-Hydroxy-2-phenyl-ethyl)-6-iodo-3-methyl-1H-pyridin-2-one
• 英文别名: 4-(1-hydroxy-2-phenylethyl)-6-iodo-3-methyl-1H-pyridin-2-one
• CAS: 356056-44-5
• 化学式: C₁₄H₁₄INO₂
• 分子量: 355.175
• InChiKey: VKUHTBLLYOVNPY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Reaction and separation methods
  申请人：——

  公开号：US20040197829A1

  公开（公告）日：2004-10-07

  A method of separating compounds that includes the steps of: tagging at least a first organic compound with a first tagging moiety to result in a first tagged compound; tagging at least a second organic compound with a second tagging moiety different from the first tagging moiety to result in a second tagged compound; and separating the first tagged compound from a mixture including the second tagged compound using a separation technique based upon differences between the first tagging moiety and the second tagging moiety. Preferably, the separation technique is based upon difference in the fluorous nature of the first tagged compound and the second tagged compound, differences in total charge between the first tagged compound and the second tagged compound, differences in size between the first tagged compound and the second tagged compound, and/or differences in polarity between the first tagged compound and the second tagged compound. The present invention also provides a method for carrying out a chemical reaction including the steps of: tagging a plurality of compounds with different tagging moieties to create tagged compounds, conducting at least one chemical reaction on a mixture of the tagged compounds to produce a mixture of tagged products, and separating the mixture of tagged products by a separation technique based upon differences in the tagging moieties.

  一种分离化合物的方法，包括以下步骤：使用第一标记基团对至少一个第一有机化合物进行标记，得到第一标记化合物；使用与第一标记基团不同的第二标记基团对至少一个第二有机化合物进行标记，得到第二标记化合物；并使用基于第一标记基团和第二标记基团之间差异的分离技术从包含第二标记化合物的混合物中分离出第一标记化合物。优选地，该分离技术基于第一标记化合物和第二标记化合物之间的氟亲性差异、总电荷差异、大小差异和/或极性差异。本发明还提供了一种进行化学反应的方法，包括以下步骤：使用不同标记基团对多种化合物进行标记，创建标记化合物，对标记化合物的混合物进行至少一种化学反应，产生标记产物的混合物，并使用基于标记基团差异的分离技术分离标记产物的混合物。
• REACTION AND SEPARATION METHODS
  申请人：Curran Dennis P.

  公开号：US20100018920A1

  公开（公告）日：2010-01-28

  A method of separating compounds that includes the steps of: tagging at least a first organic compound with a first tagging moiety to result in a first tagged compound; tagging at least a second organic compound with a second tagging moiety different from the first tagging moiety to result in a second tagged compound; and separating the first tagged compound from a mixture including the second tagged compound using a separation technique based upon differences between the first tagging moiety and the second tagging moiety. Preferably, the separation technique is based upon difference in the fluorous nature of the first tagged compound and the second tagged compound, differences in total charge between the first tagged compound and the second tagged compound, differences in size between the first tagged compound and the second tagged compound, and/or differences in polarity between the first tagged compound and the second tagged compound. The present invention also provides a method for carrying out a chemical reaction including the steps of: tagging a plurality of compounds with different tagging moieties to create tagged compounds, conducting at least one chemical reaction on a mixture of the tagged compounds to produce a mixture of tagged products, and separating the mixture of tagged products by a separation technique based upon differences in the tagging moieties.

  一种分离化合物的方法，包括以下步骤：将至少第一有机化合物用第一标记基团标记，得到第一标记化合物；将至少第二有机化合物用与第一标记基团不同的第二标记基团标记，得到第二标记化合物；并使用基于第一标记基团和第二标记基团之间差异的分离技术，将包括第二标记化合物的混合物中的第一标记化合物分离出来。最好，分离技术基于第一标记化合物和第二标记化合物之间氟烷性质的差异、总电荷的差异、大小的差异和/或极性的差异。本发明还提供了一种进行化学反应的方法，包括以下步骤：用不同的标记基团标记多种化合物，创建标记化合物；在标记化合物的混合物上进行至少一种化学反应，产生标记产物的混合物，并使用基于标记基团差异的分离技术将标记产物的混合物分离出来。
• US6749756B1
  申请人：——

  公开号：US6749756B1

  公开（公告）日：2004-06-15