(6R,6aS,14aR)-methyl 6,14a-dihydroxy-11-((3R,4R,5R,6S)-4-hydroxy-3,5-dimethoxy-6-methyltetrahydro-2H-pyran-2-ylamino)-1,6a,8-trimethoxy-3-methyl-7,9,12,14-tetraoxo-5,6,6a,7,9,12,14,14a-octahydrobenzo[a]tetracene-2-carboxylate | 1353657-90-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 并四苯
• 英文名称: (6R,6aS,14aR)-methyl 6,14a-dihydroxy-11-((3R,4R,5R,6S)-4-hydroxy-3,5-dimethoxy-6-methyltetrahydro-2H-pyran-2-ylamino)-1,6a,8-trimethoxy-3-methyl-7,9,12,14-tetraoxo-5,6,6a,7,9,12,14,14a-octahydrobenzo[a]tetracene-2-carboxylate
• 英文别名: methyl (6R,6aS,14aR)-6,14a-dihydroxy-11-[[(3R,4R,5R,6S)-4-hydroxy-3,5-dimethoxy-6-methyloxan-2-yl]amino]-1,6a,8-trimethoxy-3-methyl-7,9,12,14-tetraoxo-5,6-dihydrobenzo[a]tetracene-2-carboxylate
• CAS: 1353657-90-5
• 化学式: C₃₆H₃₉NO₁₅
• 分子量: 725.703
• InChiKey: NOZMIPNHNAFWTR-RLNPVHBASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  52
• 可旋转键数：
  9
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  223
• 氢给体数：
  4
• 氢受体数：
  16

文献信息

• NOVEL ANTIBACTERIAL COMPOUNDS, METHODS OF MAKING THEM, AND USES THEREOF
  申请人：CARR GRANT J.

  公开号：US20120010163A1

  公开（公告）日：2012-01-12

  The present invention relates to novel therapeutics with antibacterial activity, processes for their preparation, and pharmaceutical, veterinary and nutritional compositions containing them as active ingredients. The present invention also relates to uses of the novel therapeutics, for example, as medicants or food additives in the treatment of bacterial infections or to aid body mass gain in a subject.

  本发明涉及具有抗菌活性的新型治疗药物，其制备过程以及包含它们作为活性成分的药用、兽医和营养组合物。本发明还涉及新型治疗药物的用途，例如，作为药物或食品添加剂用于治疗细菌感染或帮助受试者增加体重。
• US8754054B2
  申请人：——

  公开号：US8754054B2

  公开（公告）日：2014-06-17