N-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-4-methylnaphthalene-1-sulfonamide | 1132771-52-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-4-methylnaphthalene-1-sulfonamide
• 英文别名: N-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-4-methylnaphthalene-1-sulfonamide
• CAS: 1132771-52-8
• 化学式: C₂₃H₂₅N₃O₂S
• 分子量: 407.536
• InChiKey: PUAHHJURWAVEHD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  73.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Naphthyl-substituted sulfonamides
  申请人：Laboratorios del Dr. Esteve S.A.

  公开号：EP2036888A1

  公开（公告）日：2009-03-18

  The present application relates to naphtyl substituted sulfonamides according to general formula (I) with 5-HT6 receptor affinity, a medicament comprising a said compound, and the use of one of said compounds for the manufacture of a medicament.

  本申请涉及具有5-HT6受体亲和力的萘基取代磺胺基化合物，其通式为(I)，包括所述化合物的药物、以及利用所述化合物之一制备药物的用途。
• [EN] NAPHTYL-SUBSTITUTED SULFONAMIDES<br/>[FR] SULFONAMIDES À SUBSTITUTION NAPHTYLE
  申请人：ESTEVE LABOR DR

  公开号：WO2009036955A1

  公开（公告）日：2009-03-26

  The present application relates to naphtyl substituted sulfonamides according to general formula (I) with 5-HT6 receptor affinity, a medicament comprising a said compound, and the use of one of said compounds for the manufacture of a medicament.