Acetic acid--2-methylnaphthalene-1,4-diol (1/1) | 62942-02-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Acetic acid--2-methylnaphthalene-1,4-diol (1/1)
• 英文别名: acetic acid;2-methylnaphthalene-1,4-diol
• CAS: 62942-02-3
• 化学式: C13H14O4
• 分子量: 234.25
• InChiKey: HXCMGUXRBKICAV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.65
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Method for producing quinone compound
  申请人：Tomiyama Tadashi

  公开号：US20070060761A1

  公开（公告）日：2007-03-15

  A method for producing menatetrenone that does not have a deleterious influence on the environment, that is safe even when applied to large-scale production, and that is also simple to operate, wherein a compound represented by the following formula (1) is produced by treating with an oxygen source, and without the addition of an additive other than water or aqueous sodium chloride solution, a reaction solution consisting essentially of a solution of a compound represented by the following formula (2) dissolved in a solvent:

  一种生产甲萘三酮的方法，该方法不会对环境产生有害影响，即使应用于大规模生产也很安全，而且操作简单。该方法通过用氧源处理以下式子（1）所表示的化合物，而不添加水或水溶性氯化钠溶液以外的添加剂，处理以下式子（2）所表示的化合物在溶剂中溶解的反应溶液，从而制备甲萘三酮。
• Purification method of crude product
  申请人：EISAI CHEMICAL CO., LTD.

  公开号：EP0592962A1

  公开（公告）日：1994-04-20

  Disclosed herein is a purification method of a crude product by column chromatography on silica gel or on a vinyl alcohol copolymer. Methanol-containing n-hexane and/or n-hexane-containing methanol is used as an eluent to elute the crude product, thereby obtaining an intended product with high purity and good yield. The solvents recovered from the effluent can be regenerated without any trouble such as rectification and a great cost by mixing them under stirring and then separating the resulting upper and lower layer from each other. The column used can also be reused again and again by washing with methanol. The separation and purification method is excellent in separation efficiency, operation efficiency and economical efficiency.

  本发明公开了一种在硅胶或乙烯醇共聚物上通过柱层析提纯粗产品的方法。使用含甲醇的正己烷和/或含正己烷的甲醇作为洗脱液洗脱粗产品，从而获得纯度高、收率好的预期产品。从流出物中回收的溶剂可以在搅拌下混合，然后将上层和下层相互分离，这样就可以再生，而不需要任何麻烦，例如整顿，也不需要花费大量成本。使用过的色谱柱还可以通过甲醇清洗反复使用。这种分离纯化方法在分离效率、操作效率和经济效益方面都非常出色。
• US5547580A
  申请人：——

  公开号：US5547580A

  公开（公告）日：1996-08-20
• US7439402B2
  申请人：——

  公开号：US7439402B2

  公开（公告）日：2008-10-21