2-methyl-7-(2-naphthyl)-3-[(3R)-piperidin-3-yl]-3H-imidazo[4,5-b]pyridine | 1127117-97-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-methyl-7-(2-naphthyl)-3-[(3R)-piperidin-3-yl]-3H-imidazo[4,5-b]pyridine
• 英文别名: 2-methyl-7-naphthalen-2-yl-3-[(3R)-piperidin-3-yl]imidazo[4,5-b]pyridine
• CAS: 1127117-97-8
• 化学式: C₂₂H₂₂N₄
• 分子量: 342.443
• InChiKey: FVJLUDLHABIXGY-LJQANCHMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  26
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  42.7
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• IMIDAZOPYRIDINE ANALOGS AND THEIR USE AS AGONISTS OF THE WNT-BETA-CATENIN CELLULAR MESSAGING SYSTEM
  申请人：Lundquist, IV Joseph Theodore

  公开号：US20090069319A1

  公开（公告）日：2009-03-12

  The present invention relates to imidazopyridine analogs, methods of making imidazopyridine analogs, compositions comprising an imidazopyridine analog, and methods for treating canonical Wnt-β-catenin cellular messaging system-related disorders comprising administering to a subject in need thereof an effective amount of an imidazopyridine analog.

  本发明涉及咪唑吡啶类似物，制备咪唑吡啶类似物的方法，包含咪唑吡啶类似物的组合物，以及治疗经典Wnt-β-catenin细胞信使系统相关疾病的方法，包括向需要的受试者施用有效量的咪唑吡啶类似物。
• Graft copolymers, their preparation and use in capillary electrophoresis
  申请人：Lau N.K. Aldrich

  公开号：US20050234166A1

  公开（公告）日：2005-10-20

  The invention relates to graft copolymers, their preparation, and compositions, such as electrophoresis separation media, containing the same; also to ultra-high molecular weight poly(N,N-dimethylacrylamide) (“poly(DMA)”) polymers, their preparation, and compositions, such as electrophoresis separation media, containing the same; and more particularly to supports, such as capillaries, containing these polymers and methods for separating biomolecules, especially polynucleotides, using capillary electrophoresis. The graft copolymers can be prepared by, e.g., grafting polyacrylamide units onto a poly(DMA) backbone. Separation media comprising such graft copolymers or ultra-high molecular weight poly(DMA) polymers yield superior performance in the analysis and separation of biomolecules by capillary electrophoresis.

  本发明涉及接枝共聚物、其制备方法和含有这些聚合物的组合物，如电泳分离介质；还涉及超高分子量聚（N,N-二甲基丙烯酰胺）（"聚（DMA）"）聚合物、其制备方法和含有这些聚合物的组合物，如电泳分离介质；更具体地说，涉及含有这些聚合物的支架，如毛细管，以及利用毛细管电泳分离生物大分子，特别是多核苷酸的方法。接枝共聚物可通过将聚丙烯酰胺单元接枝到聚（DMA）骨架上等方法制备。由这种接枝共聚物或超高分子量聚（DMA）聚合物组成的分离介质在利用毛细管电泳分析和分离生物分子时性能优越。
• GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS
  申请人：Applera Corporation

  公开号：EP1539846A1

  公开（公告）日：2005-06-15
• Graft Copolymers, Their Preparation And Use in Capillary Electrophoresis
  申请人：LAU Aldrich N.K.

  公开号：US20100187111A1

  公开（公告）日：2010-07-29

  The invention relates to graft copolymers, their preparation, and compositions, such as electrophoresis separation media, containing the same; also to ultra-high molecular weight poly(N,N-dimethylacrylamide) (“poly(DMA)”) polymers, their preparation, and compositions, such as electrophoresis separation media, containing the same; and more particularly to supports, such as capillaries, containing these polymers and methods for separating biomolecules, especially polynucleotides, using capillary electrophoresis. The graft copolymers can be prepared by, e.g., grafting polyacrylamide units onto a poly(DMA) backbone. Separation media comprising such graft copolymers or ultra-high molecular weight poly(DMA) polymers yield superior performance in the analysis and separation of biomolecules by capillary electrophoresis.
• US8784627B2
  申请人：——

  公开号：US8784627B2

  公开（公告）日：2014-07-22