6-[2-[1,2,3,4-Tetrahydro-2-methyl-1-(1-methylethyl)-7-isoquinolinyl]ethynyl]-2-naphthalenecarboximidamide | 1197194-02-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢异喹啉
• 英文名称: 6-[2-[1,2,3,4-Tetrahydro-2-methyl-1-(1-methylethyl)-7-isoquinolinyl]ethynyl]-2-naphthalenecarboximidamide
• 英文别名: 6-[2-(2-methyl-1-propan-2-yl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]naphthalene-2-carboximidamide
• CAS: 1197194-02-7
• 化学式: C₂₆H₂₇N₃
• 分子量: 381.5
• InChiKey: FJOUDIDTJYMKBN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  53.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• METHODS AND COMPOSITIONS FOR APPETITE CONTROL AND WEIGHT MANAGEMENT
  申请人：SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD.

  公开号：US20190167675A1

  公开（公告）日：2019-06-06

  The present invention provides methods and compositions for modulation of appetite, or for treatment of an appetite disorder or a metabolic disorder such as obesity or overweight, comprising a DEG/ENaC receptor modulator. The present invention also provides methods for identifying an agent for appetite modulation and/or weight management.