N-{(R)-4-[1-(3-Cyclopentyloxy-4-methoxyphenyl)-2-(4-pyridyl)ethyl]benzoyl}benzenesulfonamide | 192766-93-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: N-{(R)-4-[1-(3-Cyclopentyloxy-4-methoxyphenyl)-2-(4-pyridyl)ethyl]benzoyl}benzenesulfonamide
• 英文别名: N-{(R)-4-[1-(3-Cyclopentyloxy-4-methoxyphenyl)-2-(pyridin-4-yl)ethyl]benzoyl}benzenesulfonamide；N-(benzenesulfonyl)-4-[(1R)-1-(3-cyclopentyloxy-4-methoxyphenyl)-2-pyridin-4-ylethyl]benzamide
• CAS: 192766-93-1
• 化学式: C₃₂H₃₂N₂O₅S
• 分子量: 556.682
• InChiKey: NHVBPIIEWPUQTH-GDLZYMKVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  40
• 可旋转键数：
  10
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  103
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE
  申请人：President and Fellows of Harvard College

  公开号：US20150119399A1

  公开（公告）日：2015-04-30

  Disclosed are methods for stimulating or increasing β-cell replication or growth, e.g., for increasing insulin secretion, and methods of treating disorders such as diabetes, as well as related compositions and formulations.