(+)-(R,R)-1,2-diphenyl-N,N'-bis(2-hydroxy-2-methylpropyl)ethylenediamine | 1108617-14-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: (+)-(R,R)-1,2-diphenyl-N,N'-bis(2-hydroxy-2-methylpropyl)ethylenediamine
• CAS: 1108617-14-6
• 化学式: C₂₂H₃₂N₂O₂
• 分子量: 356.508
• InChiKey: UQIBBQHJRAIDKK-WOJBJXKFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.19
• 重原子数：
  26.0
• 可旋转键数：
  9.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  64.52
• 氢给体数：
  4.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  (+)-(R,R)-1,2-diphenyl-N,N'-bis(2-hydroxy-2-methylpropyl)ethylenediamine 、 原甲酸三乙酯 在 ammonium tetrafluoroborate 作用下， 反应 12.0h， 以90%的产率得到(+)-(4R,5R)-diphenyl-1,3-bis(2-hydroxy-2-methylpropyl)imidazolium tetrafluoroborate
  参考文献：
  名称：

  New enantiopure imidazolinium carbene ligands incorporating two hydroxy groups for Lewis acid-catalyzed diethyl zinc addition to aldehydes

  摘要：

  New enantiopure imidazolinium Carbene ligands incorporating two hydroxy functions have been synthesized from commercially available chiral amino alcohols and diamines. These ligands in combination with different metallic salts have been investigated in the diethylzinc addition to aldehydes with good yields and enantioselectivity. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2008.10.011
• 作为产物：
  描述：

  甲基环氧丙烷 、 (1R,2R)-1,2-二苯基乙二胺 以 乙醇 为溶剂， 以90%的产率得到(+)-(R,R)-1,2-diphenyl-N,N'-bis(2-hydroxy-2-methylpropyl)ethylenediamine
  参考文献：
  名称：

  New enantiopure imidazolinium carbene ligands incorporating two hydroxy groups for Lewis acid-catalyzed diethyl zinc addition to aldehydes

  摘要：

  New enantiopure imidazolinium Carbene ligands incorporating two hydroxy functions have been synthesized from commercially available chiral amino alcohols and diamines. These ligands in combination with different metallic salts have been investigated in the diethylzinc addition to aldehydes with good yields and enantioselectivity. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2008.10.011