Acetic acid (2S,4aR,6S,7R,8S,8aS)-8-acetoxy-6-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester | 916453-30-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: Acetic acid (2S,4aR,6S,7R,8S,8aS)-8-acetoxy-6-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester
• CAS: 916453-30-0
• 化学式: C₃₇H₃₆O₈S
• 分子量: 640.754
• InChiKey: JFUJWJGFJVSOIK-YTIMIXIJSA-N

反应信息

• 作为反应物：
  描述：

  Acetic acid (2S,4aR,6S,7R,8S,8aS)-8-acetoxy-6-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester 在 三乙基硅烷 、 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 以83%的产率得到Acetic acid (2S,4aR,6S,7R,8S,8aS)-7-acetoxy-6-mercapto-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester
  参考文献：
  名称：

  MMTr as an efficient anomeric S-protecting group for the synthesis of glycosyl thiols

  摘要：

  The 4-monomethoxytrityl (MMTr) group was introduced in high yields to anomeric sulfhydryl functions using commercially available MMTrCl. Significantly, it is stable to a variety of reaction conditions, including acids and bases, and is removable under very mild acidic conditions, which are compatible with the presence of a number of other acid-labile hydroxyl protecting groups. The successful preparation of seven glycosyl thiols indicates that MMTr has potential application for the synthesis of complex 1-thiosugars. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.09.003
• 作为产物：
  描述：

  2,3,4,6-四-O-乙酰基-1-硫代-BETA-D-吡喃半乳糖 在 吡啶 、 sodium methylate 、 对甲苯磺酸 作用下， 以 甲醇 为溶剂， 生成 Acetic acid (2S,4aR,6S,7R,8S,8aS)-8-acetoxy-6-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester
  参考文献：
  名称：

  MMTr as an efficient anomeric S-protecting group for the synthesis of glycosyl thiols

  摘要：

  The 4-monomethoxytrityl (MMTr) group was introduced in high yields to anomeric sulfhydryl functions using commercially available MMTrCl. Significantly, it is stable to a variety of reaction conditions, including acids and bases, and is removable under very mild acidic conditions, which are compatible with the presence of a number of other acid-labile hydroxyl protecting groups. The successful preparation of seven glycosyl thiols indicates that MMTr has potential application for the synthesis of complex 1-thiosugars. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.09.003