1-Ethoxy-3-(piperazin-1-yl)propan-2-ol | 54469-46-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1-Ethoxy-3-(piperazin-1-yl)propan-2-ol
• 英文别名: 1-ethoxy-3-piperazin-1-ylpropan-2-ol
• CAS: 54469-46-4
• 化学式: C₉H₂₀N₂O₂
• mdl: MFCD19597916
• 分子量: 188.27
• InChiKey: FKRHIKHPLLIOLR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  乙基缩水甘油基醚 、 1-Ethoxy-3-(piperazin-1-yl)propan-2-ol 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  Mislyuk, O. A.; Shibaev, V. I.; V'yunov, K. A., Journal of Organic Chemistry USSR (English Translation), 1986, vol. 22, # 12, p. 2247 - 2252

  摘要：

  DOI：
• 作为产物：
  描述：

  哌嗪 、 乙基缩水甘油基醚 以 甲醇 为溶剂， 生成 1-Ethoxy-3-(piperazin-1-yl)propan-2-ol
  参考文献：
  名称：

  Mislyuk, O. A.; Shibaev, V. I.; V'yunov, K. A., Journal of Organic Chemistry USSR (English Translation), 1986, vol. 22, # 12, p. 2247 - 2252

  摘要：

  DOI：

文献信息

• Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine
  申请人：Nektar Therapeutics

  公开号：US10189859B2

  公开（公告）日：2019-01-29

  The instant disclosure relates to (among other things) compounds that are derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine. The compounds provided possess unique effects and differences over other phenyltriazines known in the art.

  本公开涉及 6-(2,3-二氯苯基)-1,2,4-三嗪-5-胺衍生物的化合物。与本领域已知的其他苯基三嗪相比，所提供的化合物具有独特的效果和差异。
• Dendritic Polymers With Enhanced Amplification and Interior Functionality
  申请人：Tomalia A. Donald

  公开号：US20070298006A1

  公开（公告）日：2007-12-27

  Dendritic polymers with enhanced amplification and interior functionality are disclosed. These dendritic polymers are made by use of fast, reactive ring-opening chemistry (or other fast reactions) combined with the use of branch cell reagents in a controlled way to rapidly and precisely build dendritic structures, generation by generation, with cleaner chemistry, often single products, lower excesses of reagents, lower levels of dilution, higher capacity method, more easily scaled to commercial dimensions, new ranges of materials, and lower cost. The dendritic compositions prepared have novel internal functionality, greater stability (e.g., thermal stability and less or no reverse Michael's reaction), and reach encapsulation surface densities at lower generations. Unexpectedly, these reactions of polyfunctional branch cell reagents with polyfunctional cores do not create cross-linked materials. Such dendritic polymers are useful as demulsifiers for oil/water emulsions, wet strength agents in the manufacture of paper, proton scavengers, polymers, nanoscale monomers, calibration standards for electron microscopy, making size selective membranes, and agents for modifying viscosity in aqueous formulations such as paint. When these dendritic polymers have a carried material associated with their surface and/or interior, then these dendritic polymers have additional properties for carrying materials due to the unique characteristics of the dendritic polymer, such as for drug delivery, transfection, and diagnostics.
• DERIVATIVES OF 6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZIN-5-AMINE
  申请人：Nektar Therapeutics

  公开号：US20170066782A1

  公开（公告）日：2017-03-09

  The instant disclosure relates to (among other things) compounds that are derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine. The compounds provided possess unique effects and differences over other phenyltriazines known in the art.
• US7985424B2
  申请人：——

  公开号：US7985424B2

  公开（公告）日：2011-07-26
• Mislyuk, O. A.; Shibaev, V. I.; V'yunov, K. A., Journal of Organic Chemistry USSR (English Translation), 1986, vol. 22, # 12, p. 2247 - 2252
  作者：Mislyuk, O. A.、Shibaev, V. I.、V'yunov, K. A.

  DOI：——

  日期：——