cis-dichloro-{4,4'-di-{5''-(F-hexyl)-4''-pentenyloxycarbonyl}-2,2'-bipyridine}-platinum(II) | 149883-76-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯并吡啶类
• 英文名称: cis-dichloro-{4,4'-di-{5''-(F-hexyl)-4''-pentenyloxycarbonyl}-2,2'-bipyridine}-platinum(II)
• CAS: 149883-76-1
• 化学式: C₃₄H₂₂Cl₂F₂₆N₂O₄Pt
• 分子量: 1282.5
• InChiKey: DPIUCYDUBLARGJ-UHFFFAOYSA-L

反应信息

• 作为产物：
  描述：

  potassium tetrachloroplatinate(II) 、 (E)-4,4'-Bis<<<5''-(F-hexyl)-4''-pentenyl>oxy>carbonyl>-2,2'-bipyridine 在 四乙基氯化铵 作用下， 以 二氯甲烷 、 水 为溶剂， 以55%的产率得到cis-dichloro-{4,4'-di-{5''-(F-hexyl)-4''-pentenyloxycarbonyl}-2,2'-bipyridine}-platinum(II)
  参考文献：
  名称：

  Synthesis and characterization of amphiphilic platinum and palladium complexes linked to perfluoroalkylated side-chain disubstituted bipyridines

  摘要：

  The synthesis and characterization of three series of cis-dichloro-[4,4'-bis[(F-alkyl)alkyl]-2,2'-bipyridine], cis-dichloro-[4,4'-bis[(F-alkyl)alkyloxycarbonyl]-2,2'-bipyridine] and cis-dichloro-[4,4'-bis[[2"-(F-alkyl)ethenyl]alkyl-oxycarbonyl]-2,2'-bipyridine]-platinum(II) or -palladium(II) complexes are described. These new amphiphilic perfluoroalkylated derivatives, as potential antitumor agents, were designed to be incorporated into liposomes and, more particularly, into injectable fluorocarbon emulsions.

  DOI：

  10.1016/s0020-1693(00)82670-5