2-(4-Bromo-2-methylphenyl)propanoicacid | 1501145-09-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 2-(4-Bromo-2-methylphenyl)propanoicacid
• 英文别名: 2-(4-bromo-2-methylphenyl)propanoic acid
• CAS: 1501145-09-0
• 化学式: C₁₀H₁₁BrO₂
• 分子量: 243.1
• InChiKey: GBGFZABEEFTHNR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Dialkyl-halogenophenyl-substituted ketoenols
  申请人：——

  公开号：US20020022575A1

  公开（公告）日：2002-02-21

  The present invention relates to new compounds of the formula (I) 1 in which X represents alkyl, Y represents halogen or alkyl and Z represents halogen or alkyl, with the proviso that one of the radicals Y and Z always represents halogen and the other alkyl, Het represents one of the groups 2 in which A, B, D and G have the meanings given in the description, a plurality of processes for their preparation and their use as pesticides and herbicides.

  本发明涉及公式（I）的新化合物：1 其中，X代表烷基，Y代表卤素或烷基，Z代表卤素或烷基，但是Y和Z中的一个始终代表卤素，另一个代表烷基，Het代表下列组之一：2 其中，A、B、D和G的含义如描述中所给，涉及多种制备过程以及它们作为杀虫剂和除草剂的用途。
• Biaryl urea derivative or salt thereof and preparation process and use for the same
  申请人：Fudan University

  公开号：US10647665B2

  公开（公告）日：2020-05-12

  The present invention discloses a biaryl urea RORγt inhibitor, and specifically relates to a biaryl urea derivative, as represented by formula I, with an RORγt inhibiting activity, and a preparation process thereof, and a pharmaceutical composition comprising the compound. Further disclosed is use of the compound for treating an RORγt-related disease.

  本发明公开了一种双芳基脲 RORγt 抑制剂，具体涉及一种由式 I 表示的具有 RORγt 抑制活性的双芳基脲衍生物及其制备工艺，以及包含该化合物的药物组合物。进一步公开了该化合物用于治疗 RORγt 相关疾病的用途。
• N-Heterocycl phenyl-substituted cyclic ketoenols
  申请人：Fischer Reiner

  公开号：US20060166829A1

  公开（公告）日：2006-07-27

  The invention relates to novel N-heterocyclylphenyl-substituted cyclic ketoenols of the formula (I) in which CKE, W, X, Y and Z are as defined above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides and/or microbicides. Moreover, the invention relates to selective herbicidal compositions comprising firstly the N-heterocyclylphenyl-substituted cyclic ketoenols and secondly a compound which improves crop plant tolerance.

  本发明涉及式 (I) 的新型 N-杂环苯基取代环酮烯醇，其中 CKE、W、X、Y 和 Z 如上文所定义。 其中 CKE、W、X、Y 和 Z 如上定义，涉及制备它们的多种工艺和中间体，以及它们作为杀虫剂和/或除草剂和/或杀微生物剂的用途。此外，本发明还涉及选择性除草组合物，该组合物首先包含 N-杂环苯基取代的环酮烯醇，其次包含一种可提高作物耐受性的化合物。
• BIARYL UREA DERIVATIVE OR SALT THEREOF, AND MANUFACTURING AND APPLICATION OF SAME
  申请人：Fudan University

  公开号：EP3476829B1

  公开（公告）日：2021-12-15
• N-HETEROCYCLYLPHENYL-SUBSTITUTED CYCLIC KETOENOLS
  申请人：Fischer Reiner

  公开号：US20100267964A1

  公开（公告）日：2010-10-21

  The invention relates to novel intermediates for the preparation of N-heterocyclylphenyl-substituted cyclic ketoenols of the formula (I) in which CKE, W, X, Y and Z are as defined in the disclosure.