butyl 1-[2-[di(propan-2-yl)amino]ethylcarbamoyl]-6-phenylmethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylate | 373634-32-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢异喹啉
• 英文名称: butyl 1-[2-[di(propan-2-yl)amino]ethylcarbamoyl]-6-phenylmethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylate
• CAS: 373634-32-3
• 化学式: C₃₀H₄₃N₃O₄
• 分子量: 509.689
• InChiKey: MNEYDBMLOMXRDA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  37
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  71.1
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• CARBAMOYLBENZOTRIAZOLE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES
  申请人：Petry Stefan

  公开号：US20080287503A1

  公开（公告）日：2008-11-20

  The invention relates to carbamoylbenzotriazole derivatives of general formula (I), which are defined as cited in the description, to their pharmaceutically applicable salts and to their use as medicaments.

  这项发明涉及一般式(I)的氨基甲酰基苯并三唑衍生物，其在描述中被定义，以及它们的药用盐和作为药物的用途。
• TRIAZOLOPYRIDINE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES
  申请人：Petry Stefan

  公开号：US20090030011A1

  公开（公告）日：2009-01-29

  The invention relates to triazolopyridine derivatives of general formula (I), which are defined as cited in the description, to their pharmaceutically applicable salts and to their use as medicaments.

  这项发明涉及一般式(I)的三唑吡啶衍生物，其定义如描述中所引用的，以及它们的药用盐和作为药物的用途。
• PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS
  申请人：KEIL Stefanie

  公开号：US20090325942A1

  公开（公告）日：2009-12-31

  The invention relates to compounds of the formula 1, wherein R1, R2, R3, R4, R5, R6, R7, A and B are as defined herein, the pharmaceutical compositions and the uses as pharmaceuticals.

  这项发明涉及公式1的化合物，其中R1、R2、R3、R4、R5、R6、R7、A和B如本文所定义，以及作为药物的药物组合物和用途。
• IMIDAZOLIDINE CARBOXAMIDE DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS
  申请人：ZOLLER Gerhard

  公开号：US20100105719A1

  公开（公告）日：2010-04-29

  The present invention relates to imidazolidinecarboxamide derivatives of the general formula I, wherein R, R1, R2, X and Y are as defined herein, or pharmaceutically usable salts thereof and the use thereof as medicinal substances.

  本发明涉及一般式I的咪唑啉羧酰胺衍生物，其中R、R1、R2、X和Y如本文所定义，或其药用盐以及其作为药用物质的用途。
• Diacyl indazole derivatives as lipase and phospholipase inhibitors
  申请人：Zoller Gerhard

  公开号：US20080287448A1

  公开（公告）日：2008-11-20

  The invention relates to diacyl indazole derivatives of general formulae (I) or (II) and to the pharmaceutically acceptable salts thereof: Wherein X, R1 and R2 are as defined herein. The invention also relates to the use of these compounds as pharmaceutical products.

  该发明涉及一般式(I)或(II)的二酰基吲唑衍生物以及其药用可接受的盐：其中X，R1和R2如本文所定义。该发明还涉及将这些化合物用作药物产品。