4-(4-chloro-2-methyl-phenylazo)-3-hydroxy-naphthalene-2,7-disulfonyl chloride | 109647-50-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-(4-chloro-2-methyl-phenylazo)-3-hydroxy-naphthalene-2,7-disulfonyl chloride
• 英文别名: 4-(4-Chlor-2-methyl-phenylazo)-3-hydroxy-naphthalin-2,7-disulfonylchlorid
• CAS: 109647-50-9
• 化学式: C₁₇H₁₁Cl₃N₂O₅S₂
• 分子量: 493.776
• InChiKey: LCHRIVJYZAOZLS-QURGRASLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.78
• 重原子数：
  29.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  113.23
• 氢给体数：
  1.0
• 氢受体数：
  7.0

反应信息

• 作为产物：
  描述：

  2-萘酚-3,6-二磺酸 、 alkaline earth salt of/the/ methylsulfuric acid 生成 4-(4-chloro-2-methyl-phenylazo)-3-hydroxy-naphthalene-2,7-disulfonyl chloride
  参考文献：
  名称：

  亚硫酰氯催化生产羧酸和磺酸氯的方法†

  摘要：

  Abstract Sulphonic acids and carboxylic acids which do not react with thionyl chloride under normal conditions give the corresponding acid chlorides with this reagent in excellent yields when dimethylformamide is present as a catalyst. The reaction of thionylchloride with dimethylformamide yields the corresponding amide chloride which has not been isolated before in pure state. This amide chloride reacts with acids under formation of acid chlorides. The mechanism of these reactions is discussed.

  DOI：

  10.1002/hlca.19590420526