ethyl 2-{14,14,15-trimethyl-2,3,5,6,8,9,14,15-octahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]isoquinolin-12(13H)-ylidene}ethanoate | 1608128-83-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢异喹啉
• 英文名称: ethyl 2-{14,14,15-trimethyl-2,3,5,6,8,9,14,15-octahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]isoquinolin-12(13H)-ylidene}ethanoate
• CAS: 1608128-83-1
• 化学式: C₂₂H₃₁NO₆
• 分子量: 405.491
• InChiKey: LQWXCXGXBJUQIV-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  ethyl 2-{14,14,15-trimethyl-2,3,5,6,8,9,14,15-octahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]isoquinolin-12(13H)-ylidene}ethanoate 在 硫酸 作用下， 反应 2.5h， 以74%的产率得到12,14,14,15-tetramethyl-2,3,5,6,8,9,14,15-octahydro[1,4,7,10]tetraoxacyclododecino[2,3-g]isoquinoline
  参考文献：
  名称：

  Synthesis of Podands of the 3,4-dihydroisoquinoline series

  摘要：

  Podands containing 3,4-dihydroisoquinoline fragments were synthesized by reactions of 1,1'-{ethane-1,2-diylbis[oxy(3-methoxybenzene-4,1-diyl)]}bis(2-methylpropan-1-ol) and 1-(2-ethoxyethoxy)-2-methoxy-4-(2-methylprop-1-en-1-yl)benzene with ethyl cyanoacetate and methyl thiocyanate in concentrated sulfuric acid. Likewise, 1-substituted 3,4-dihydroisoquinolines having a crown ether fragment were obtained from 4-acetylbenzo-12-crown-4.

  DOI：

  10.1134/s1070428014030130
• 作为产物：
  描述：

  、 氰乙酸乙酯 在 硫酸 作用下， 反应 1.5h， 以46%的产率得到ethyl 2-{14,14,15-trimethyl-2,3,5,6,8,9,14,15-octahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]isoquinolin-12(13H)-ylidene}ethanoate
  参考文献：
  名称：

  Synthesis of Podands of the 3,4-dihydroisoquinoline series

  摘要：

  Podands containing 3,4-dihydroisoquinoline fragments were synthesized by reactions of 1,1'-{ethane-1,2-diylbis[oxy(3-methoxybenzene-4,1-diyl)]}bis(2-methylpropan-1-ol) and 1-(2-ethoxyethoxy)-2-methoxy-4-(2-methylprop-1-en-1-yl)benzene with ethyl cyanoacetate and methyl thiocyanate in concentrated sulfuric acid. Likewise, 1-substituted 3,4-dihydroisoquinolines having a crown ether fragment were obtained from 4-acetylbenzo-12-crown-4.

  DOI：

  10.1134/s1070428014030130