5-Phenylpyrazoline | 2227272-81-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 5-Phenylpyrazoline
• 英文别名: 3-phenyl-2,3-dihydro-1H-pyrazole
• CAS: 2227272-81-1
• 化学式: C₉H₁₀N₂
• 分子量: 146.19
• InChiKey: FZDDXQDZUIPTNT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Production Process of cyclopropylphenol derivatives
  申请人：Tsukamoto Yoshihisa

  公开号：US20090054681A1

  公开（公告）日：2009-02-26

  A process for producing a cyclopropylphenol represented by of formula (10): wherein R 1 , R 2 , R 3 and R 4 each may represent a hydrogen; Z represents a hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl or phenyl; and Y 1 , Y 2 and Y 3 each may represent a hydrogen; by reacting a compound of formula (7): wherein X represents a halogen; and V represents a hydrogen or —W—R 5 , with a metal, metal salt or organometallic compound of formula (8): M 2 to obtain a compound of formula (9): and obtaining a compound represented by general of formula (10) by hydrolysis in the case wherein V represents —W—R 5 , wherein W is CO, SO or SO 2 and R 5 is alkyl, haloalkyl, cycloalkyl, alkenyl, alkynyl, phenyl, alkoxy or haloalkoxy.

  一种生产环丙基酚的方法，其化学式表示为(10): 其中，R1、R2、R3和R4均可代表氢原子；Z代表氢原子、烷基、烯基、炔基、环烷基或苯基；Y1、Y2和Y3均可代表氢原子。该方法通过将化合物(7)： 其中，X代表卤素；V代表氢原子或-W-R5，与化合物(8)： M2代表金属、金属盐或有机金属化合物，反应得到化合物(9)： 在V代表-W-R5的情况下，通过水解得到化学式为(10)的化合物，其中W为CO、SO或SO2，R5为烷基、卤代烷基、环烷基、烯基、炔基、苯基、烷氧基或卤代烷氧基。
• PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE
  申请人：Sankyo Agro Company, Limited

  公开号：EP1880987A1

  公开（公告）日：2008-01-23

  An object of the present invention is to find a method for easily synthesizing cyclopropylphenol derivatives. The object of the present invention is to find a process for producing a cyclopropylphenol derivative represented by general formula (10): [wherein R1, R2, R3 and R4 each independently represent a hydrogen atom or the like; Z represents a hydrogen atom or the like; and Y1, Y2 and Y3 each independently represent a hydrogen atom or the like]; and solved by the process comprising reacting a compound represented by general formula (7): [wherein each of the symbols are the same as previously defined; X represents a halogen atom; and V represents a hydrogen atom or the like], with a metal, metal salt or organometallic compound represented by general formula (8): M2 to obtain a compound represented by general formula (9): [wherein each of the symbols are the same as previously defined] and obtaining a compound represented by general formula (10) by hydrolysis in the case V represents the group, -W-R5.

  本发明的目的是找到一种易于合成环丙基苯酚衍生物的方法。本发明的目的是找到一种生产通式（10）所代表的环丙基苯酚衍生物的工艺： [其中 R1、R2、R3 和 R4 各自独立地代表氢原子或类似物；Z 代表氢原子或类似物；Y1、Y2 和 Y3 各自独立地代表氢原子或类似物]； 并通过使通式 (7) 所代表的化合物发生反应的过程来解决： [其中各符号与前面定义的相同；X 代表卤素原子；V 代表氢原子或类似物]、 用通式（8）代表的金属、金属盐或有机金属化合物：M2，得到通式（9）所代表的化合物： [在 V 代表基团-W-R5 的情况下，通过水解得到通式（10）代表的化合物。
• US7629494B2
  申请人：——

  公开号：US7629494B2

  公开（公告）日：2009-12-08
• [EN] EPOXIDATION OF ALPHA, BETA-UNSATURATED KETONES<br/>[FR] EPOXYDATION DE CETONES $G(A),$G(B)-INSATUREES
  申请人：ESTEVE LABOR DR

  公开号：WO2007000329A2

  公开（公告）日：2007-01-04

  [EN] The invention relates to the stereoselective epoxidation of a,ß-unsaturated ketones bearing electron withdrawing substituents and to chiral 5-phenyl-4,5-dihydropyrazoles obtained therefrom.
  [FR] L'invention concerne l'époxydation stéréosélective de cétones a,ß-insaturées supportant des substituants de retrait d'électrons, ainsi que des 5-phényl-4,5-dihydropyrazoles chirales obtenues à partir de celle-ci.