Acetyl-RhoHM | 1241795-18-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: Acetyl-RhoHM
• 英文别名: N-(6'-aminospiro[1H-2-benzofuran-3,9'-xanthene]-3'-yl)acetamide
• CAS: 1241795-18-5
• 化学式: C₂₂H₁₈N₂O₃
• 分子量: 358.397
• InChiKey: AGXWNYYVLATHDH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  27
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  73.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• FLUORESCENT PROBE FOR USE IN MEASUREMENT OF PROTEASE
  申请人：The University of Tokyo

  公开号：EP2399920B1

  公开（公告）日：2015-03-25
• FLUORESCENT PROBE FOR MEASURING PROTEASE
  申请人：Nagano Tetsuo

  公开号：US20120052518A1

  公开（公告）日：2012-03-01

  A compound represented by the formula (I) or a salt thereof (R 1 represents hydrogen atom, or a substituent; R 2 to R 7 represent hydrogen atom, hydroxyl group, an alkyl group, or a halogen atom; R 8 and R 9 represent hydrogen atom, or an alkyl group; X represents a C 1 -C 3 alkylene group; and R 10 represents an acyl group), which promptly causes a structural change from a non-fluorescent closed ring structure to a strongly fluorescent open ring structure by hydrolysis of an acyl group, and is useful as a fluorescent probe for measuring a protease showing superior suitability for quantification.
• US8461358B2
  申请人：——

  公开号：US8461358B2

  公开（公告）日：2013-06-11