| 1116450-21-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• CAS: 1116450-21-5
• 化学式: C₁₉H₃₉N₂O₂
• 分子量: 327.531
• InChiKey: IIWBOPJAFPHJAE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  23
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  36.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,2-二甲基丁炔酯 、 4-氨基-TEMPO 在 calcium(II) trifluoromethanesulfonate 作用下， 以 1,4-二氧六环 为溶剂， 140.0 ℃ 、300.01 kPa 条件下， 反应 0.33h， 以76%的产率得到
  参考文献：
  名称：

  Microwave-assisted synthesis of amphiphilic spin probes

  摘要：

  New amphiphilic nitroxide spin probes have been synthesized. The key reaction is based on microwave-assisted epoxide ring opening with amines as nucleophiles using Calcium triflouromethanesulfonate as a catalyst. High yields, in short reaction times, were obtained without any detectable nitroxide decomposition. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.11.065

文献信息

• Microwave-assisted synthesis of amphiphilic spin probes
  作者：Anja Hafner、Martina Hrast、Slavko Pečar、Janez Mravljak

  DOI：10.1016/j.tetlet.2008.11.065

  日期：2009.2

  New amphiphilic nitroxide spin probes have been synthesized. The key reaction is based on microwave-assisted epoxide ring opening with amines as nucleophiles using Calcium triflouromethanesulfonate as a catalyst. High yields, in short reaction times, were obtained without any detectable nitroxide decomposition. (c) 2008 Elsevier Ltd. All rights reserved.