dimethyl 5,6,7-trimethoxy-4-vinyl-3,4-dihydronaphthalene-2,2(1H)-dicarboxylate | 1013916-91-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: dimethyl 5,6,7-trimethoxy-4-vinyl-3,4-dihydronaphthalene-2,2(1H)-dicarboxylate
• 英文别名: dimethyl 4-ethenyl-5,6,7-trimethoxy-3,4-dihydro-1H-naphthalene-2,2-dicarboxylate
• CAS: 1013916-91-0
• 化学式: C₁₉H₂₄O₇
• 分子量: 364.395
• InChiKey: YFPZPCMNMYPLGF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  26
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  80.3
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  dimethyl 2-(1,2-butadienyl)-2-(3,4,5-trimethoxybenzyl)malonate 在 triphenylphosphite gold(I) chloride silver hexafluoroantimonate 作用下， 以 二氯甲烷 为溶剂， 反应 16.0h， 生成 、 dimethyl 5,6,7-trimethoxy-4-vinyl-3,4-dihydronaphthalene-2,2(1H)-dicarboxylate 、
  参考文献：
  名称：

  Gold(I)-Catalyzed Intramolecular Hydroarylation of Allenes

  摘要：

  Gold(I) complexes react with 4-allenyl arenes in an exo fashion to furnish vinyl-substituted benzocycles. Phosphite gold(I) monocations were found to be optimal, and the catalyst was tolerant of ethers, esters, and pyrroles. Reactions proceeded in unpurified solvent at room temperature.

  DOI：

  10.1021/jo7024948

文献信息

• Gold(I)-Catalyzed Intramolecular Hydroarylation of Allenes
  作者：Michael A. Tarselli、Michel R. Gagné

  DOI：10.1021/jo7024948

  日期：2008.3.1

  Gold(I) complexes react with 4-allenyl arenes in an exo fashion to furnish vinyl-substituted benzocycles. Phosphite gold(I) monocations were found to be optimal, and the catalyst was tolerant of ethers, esters, and pyrroles. Reactions proceeded in unpurified solvent at room temperature.