N,N'-[(1E,2E)-1,2-diphenylethane-1,2-diylidene]-bis-(2,6-diisopropylphenylaniline) | 1352656-09-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: N,N'-[(1E,2E)-1,2-diphenylethane-1,2-diylidene]-bis-(2,6-diisopropylphenylaniline)
• 英文别名: (1E,2E)-N¹,N²-bis(2,6-diisopropylphenyl)-1,2-diphenylethane-1,2-diimine
• CAS: 1352656-09-7
• 化学式: C₃₈H₄₄N₂
• 分子量: 528.781
• InChiKey: UTGPTMKTLUZNKE-MBIPSJRMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.12
• 重原子数：
  40.0
• 可旋转键数：
  9.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  24.72
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  N-(2,6-二异丙基苯基)甲酰胺 在 四(三苯基膦)钯 、 三乙胺 、 三氯氧磷 作用下， 以 氯仿 、 甲苯 为溶剂， 反应 6.0h， 生成 N,N'-[(1E,2E)-1,2-diphenylethane-1,2-diylidene]-bis-(2,6-diisopropylphenylaniline) 、 N-(diphenylmethylene)-2,6-diisopropylaniline
  参考文献：
  名称：

  Palladium-Catalyzed Diarylation of Isocyanides with Tetraarylleads for the Selective Synthesis of Imines and α-Diimines

  摘要：

  Using tetraaryllead compounds (PbAr4) as arylating reagents, isocyanides undergo selective diarylation in the presence of palladium catalysts such as Pd(OAc)(2) or Pd(PPh3)(4) to afford imines and/or alpha-diimines based on the isocyanide employed. With aliphatic isocyanides, imines are obtained preferentially, whereas alpha-diimines are formed in the case of electron-rich aromatic isocyanides. The differences in imine/alpha-diimine selectivity can be attributed to the stability of imidoylpalladium intermediates formed in this catalytic reaction. Compared with other arylating reagents, tetraaryllead compounds are excellent candidates for use in the selective transformations to imines and/or alpha-diimines, especially in terms of inhibiting the oligomerization of isocyanides, which results in a lower product selectivity in many transition-metal-catalyzed reactions of isocyanides.

  DOI：

  10.1021/acs.joc.9b01639

文献信息

• CARBONYLATION PROCESS
  申请人：Zoeller Joseph Robert

  公开号：US20090247783A1

  公开（公告）日：2009-10-01

  Disclosed is an improved carbonylation process for the production of carboxylic acids, carboxylic acid esters, and/or carboxylic acid anhydrides wherein a carbonylation feedstock compound selected from one or more organic oxygenates such as alcohols, ethers, and esters is contacted with carbon monoxide in the presence of a carbonylation catalyst and one or more onium compounds. The carbonylation process differs from known carbonylation processes in that a halide compound, other than the onium salt, such as a hydrogen halide (typically, hydrogen iodide) and/or an alkyl halide (typically, methyl iodide), extraneous or exogenous to the carbonylation process is not fed or supplied to the process. The process can be improved by using a bidentate ligand comprising two functional groups selected from tertiary amines and tertiary phosphines, such as 2,2′-bipyridine and diphosphine derivatives.

  本文披露了一种改进的羰基化过程，用于生产羧酸、羧酸酯和/或羧酸酐。在该过程中，选择一种或多种有机氧化物，如醇、醚和酯，作为羰基化原料化合物，并在羰基化催化剂和一种或多种离子化合物的存在下与一氧化碳接触。该羰基化过程与已知的羰基化过程不同之处在于，除了离子盐以外，不向过程中提供卤化物化合物，如氢卤化物（通常为氢碘酸）和/或烷基卤化物（通常为甲基碘化物）。该过程可以通过使用双齿配体来改进，该双齿配体包括两种从三级胺和三级膦中选择的功能基团，例如2,2'-联吡啶和二膦衍生物。
• New catalyst for homocoupling of aryl halides based on nickel complexes with diazabutadiene ligands
  作者：V. N. Valaeva、A. F. Asachenko、P. S. Kulyabin、V. R. Flid、A. Z. Voskoboinikov

  DOI：10.1134/s1070428011110236

  日期：2011.11