Methyl-bis-[2-(naphthalen-1-yloxy)-ethyl]-amine | 24104-01-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Methyl-bis-[2-(naphthalen-1-yloxy)-ethyl]-amine
• 英文别名: N-methyl-2-naphthalen-1-yloxy-N-(2-naphthalen-1-yloxyethyl)ethanamine
• CAS: 24104-01-6
• 化学式: C₂₅H₂₅NO₂
• 分子量: 371.479
• InChiKey: IVJJNFFPKBFHKN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESIN
  申请人：BIO-RAD LABORATORIES, INC.

  公开号：US20200406232A1

  公开（公告）日：2020-12-31

  Chromatography resins having anionic exchange-hydrophobic mixed mode ligands, that are useful for purifying target biomolecules using anionic exchange (i.e., where the ligand is positively charged) and hydrophobic mixed mode chromatography. The chromatography resins allow for efficient purification of target biomolecules (e.g., recombinant proteins, antibodies, antibody-drug conjugates, or antibody derivatives including, but not limited to, antibody fragments and antibody fusions) from a sample, and have been found to be useful in purifying monomeric target biomolecules from aggregate target biomolecules. In an embodiment, the chromatography resins are useful for separating antibodies from one or more components (e.g., contaminants) in the sample.