(4aR,6aR,12aS,12bR)-10-hydroxy-4,4,6a,12b-tetramethyl-2,3,4a,5,6,12a-hexahydro-1H-benzo[a]xanthen-9-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并吡喃类
• 英文名称: (4aR,6aR,12aS,12bR)-10-hydroxy-4,4,6a,12b-tetramethyl-2,3,4a,5,6,12a-hexahydro-1H-benzo[a]xanthen-9-one
• 化学式: C₂₁H₂₈O₃
• 分子量: 328.4
• InChiKey: LOCMLXSTDCXZFJ-KOUHRCEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  24
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Antimicrobial compositions for Clostridium difficile
  申请人：University of Central Florida Research Foundation, Inc.

  公开号：US10314813B2

  公开（公告）日：2019-06-11

  Clostridium difficile infects and kills 30,000-40,000 people a year in the United States. Provided herein are methods to inhibit growth and reduce the spread of C. difficile using puupehenone, a natural marine product that is excreted from some species of sponges and coral as a defense mechanism.

  在美国，艰难梭状芽孢杆菌每年感染并导致 30,000 至 40,000 人死亡。本文提供了使用普鲁苯酮抑制艰难梭菌生长和减少艰难梭菌传播的方法，普鲁苯酮是一种天然海洋产品，作为一种防御机制从某些种类的海绵和珊瑚中排出。
• ANTIMICROBIAL COMPOSITIONS FOR CLOSTRIDIUM DIFFICILE
  申请人：University of Central Florida Research Foundation, Inc.

  公开号：US20180325863A1

  公开（公告）日：2018-11-15

  Clostridium difficile infects and kills 30,000-40,000 people a year in the United States. Provided herein are methods to inhibit growth and reduce the spread of C. difficile using puupehenone, a natural marine product that is excreted from some species of sponges and coral as a defense mechanism.