Bisanhydro-ε-rhodomycinon | 115964-28-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 并四苯
• 英文名称: Bisanhydro-ε-rhodomycinon
• CAS: 115964-28-8
• 化学式: C₂₂H₁₆O₇
• 分子量: 392.365
• InChiKey: VIXDWJYWNVDIOV-UHFFFAOYSA-N

物化性质

• 沸点：
  656.0±55.0 °C(predicted)
• 密度：
  1.513±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为反应物：
  描述：

  Bisanhydro-ε-rhodomycinon 、 碘甲烷 在 potassium carbonate 作用下， 生成 4,6,11-tri-O-methyl-η-rhodomycinone
  参考文献：
  名称：

  8-Hydroxyanthracyclinones from .epsilon.-rhodomycinone

  摘要：

  epsilon-Rhodomycinone was converted into 8,9-dehydro-zeta-rhodomycinone, which gave a cis diol with osmium tetroxide and a pair of epimeric epoxides with m-chloroperbenzoic acid. Acid-catalyzed opening of the epoxides gave the corresponding trans diols. In contrast, acid treatment of the trimethyl ethers of these epoxides gave predominantly a lactone and an eta-rhodomycinone derivative, with only small amounts of the diols. None of the new rhodomycinones were active against Bacillus subtilis, but 8,9-dehydro-zeta-rhodomycinone was active in the induction of lytic phage in Escherichia coli.

  DOI：

  10.1021/jm00185a020