5'-(4-iodophenyl)-4'-[3-methyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl]-2',5'-diphenyl-2',4'-dihydro spiro-(indolin-3,3'[1,2,4]triazol)-2-one | 1606126-08-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 5'-(4-iodophenyl)-4'-[3-methyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl]-2',5'-diphenyl-2',4'-dihydro spiro-(indolin-3,3'[1,2,4]triazol)-2-one
• CAS: 1606126-08-2
• 化学式: C₂₄H₁₈IN₇OS
• 分子量: 579.424
• InChiKey: SXPOBUKFVSQWLM-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  (3Z)-3-[3-methyl-5-thioxo-1H-1,2,4-triazol-4(5H)-ylimino]indolin-2-one 、 N-(α-Chlor-benzyliden)-N'-(4-jod-phenyl)-hydrazin 在 三乙胺 作用下， 以 乙腈 为溶剂， 反应 20.0h， 以83%的产率得到5'-(4-iodophenyl)-4'-[3-methyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl]-2',5'-diphenyl-2',4'-dihydro spiro-(indolin-3,3'[1,2,4]triazol)-2-one
  参考文献：
  名称：

  Synthesis of 4′-[3-methyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl]-2′,5′-diphenyl-2′,4′-dihydro spiro[indolin-3,3′[1,2,4]triazol]-2-one derivatives

  摘要：

  In this paper 1,3-dipolar cycloaddition reaction has been studied. An efficient synthesis of 4'-[3-methyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl]-2',5'-diphenyl-2',4'-dihydro spiro(indolin-3,3'[1,2,4]triazol)-2-one derivatives using triethylamine in MeCN at room temperature is reported. The structures of the obtained compounds were confirmed by means of elemental analysis, MS and spectral (IR, H-1, and C-13 NMR) methods.

  DOI：

  10.1134/s107036321403030x