3-Diazo-5-[1-(2,3-dichloro-phenyl)-meth-(Z)-ylidene]-pyrrolidine-2,4-dione | 220069-85-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-Diazo-5-[1-(2,3-dichloro-phenyl)-meth-(Z)-ylidene]-pyrrolidine-2,4-dione
• CAS: 220069-85-2
• 化学式: C₁₁H₅Cl₂N₃O₂
• 分子量: 282.086
• InChiKey: FTUVAJYXXNATGT-DAXSKMNVSA-N

反应信息

• 作为反应物：
  描述：

  苯甲醚 、 3-Diazo-5-[1-(2,3-dichloro-phenyl)-meth-(Z)-ylidene]-pyrrolidine-2,4-dione 在 rhodium(II) acetate dimer 作用下， 反应 0.17h， 以40%的产率得到5-[1-(2,3-Dichloro-phenyl)-meth-(Z)-ylidene]-4-hydroxy-3-(4-methoxy-phenyl)-1,5-dihydro-pyrrol-2-one
  参考文献：
  名称：

  5-Arylidene-3-aryl-pyrrolidine-2,4-diones with Affinity to theN-Methyl-D-aspartate (Glycine Site) Receptor, Part I

  摘要：

  A series of new 5-arylidene 3-aryl-pyrrolidine-2,4-diones has been prepared. Their binding affinity toward the N-methyl-D-aspartate (glycine site) receptor has been measured as a basis for more derailed structure-activity relationship studies.

  DOI：

  10.1002/(sici)1521-4184(199812)331:12<389::aid-ardp389>3.0.co;2-w
• 作为产物：
  描述：

  5-(2,3-dichlorobenzylidene)-4-hydroxy-1,5-dihydropyrrol-2-one 在 对甲苯磺酰叠氮 、 三乙胺 作用下， 以 甲醇 为溶剂， 反应 3.0h， 以75%的产率得到3-Diazo-5-[1-(2,3-dichloro-phenyl)-meth-(Z)-ylidene]-pyrrolidine-2,4-dione
  参考文献：
  名称：

  5-Arylidene-3-aryl-pyrrolidine-2,4-diones with Affinity to theN-Methyl-D-aspartate (Glycine Site) Receptor, Part I

  摘要：

  A series of new 5-arylidene 3-aryl-pyrrolidine-2,4-diones has been prepared. Their binding affinity toward the N-methyl-D-aspartate (glycine site) receptor has been measured as a basis for more derailed structure-activity relationship studies.

  DOI：

  10.1002/(sici)1521-4184(199812)331:12<389::aid-ardp389>3.0.co;2-w