3-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]-5-[[(1R)-1-phenylethyl]carbamoyl]benzoic acid | 911787-37-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]-5-[[(1R)-1-phenylethyl]carbamoyl]benzoic acid
• CAS: 911787-37-6
• 化学式: C₂₈H₂₇N₃O₅S
• 分子量: 517.605
• InChiKey: GIAROTRRPAPSED-GOSISDBHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  37
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  124
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Substituted 1,2-ethylenediamines, Methods for Preparing Them and Uses Thereof
  申请人：Eickmeier Christian

  公开号：US20090325940A1

  公开（公告）日：2009-12-31

  The present invention relates to substituted 1,2-ethylenediamines of general formula (I) wherein the groups R 1 to R 15 , A, B, L, i as well as X 1 -X 4 are defined as in the specification and claims and the use thereof for the treatment of Alzheimer's disease (AD) and similar diseases.
• SUBSTITUTED 1,2-ETHYLENEDIAMINES, METHODS FOR PREPARING THEM AND USES THEREOF
  申请人：EICKMEIER Christian

  公开号：US20100204160A1

  公开（公告）日：2010-08-12

  The present invention relates to substituted 1,2-ethylenediamines of general formula (I) wherein the groups R 1 to R 15 , A, B, L, i as well as X 1 -X 4 are defined as in the specification and claims and the use thereof for the treatment of Alzheimer's disease (AD) and similar diseases.
• US7713961B2
  申请人：——

  公开号：US7713961B2

  公开（公告）日：2010-05-11