α-Benzyl-γ-acetylvaleriansaeure | 29922-84-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: α-Benzyl-γ-acetylvaleriansaeure
• 英文别名: 2-Benzyl-4-methyl-5-oxohexanoic acid
• CAS: 29922-84-7
• 化学式: C₁₄H₁₈O₃
• 分子量: 234.295
• InChiKey: WYFSGNCNJAQKMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• COMPOSITIONS FOR USE IN THE TREATMENT OF BCAT1-MEDIATED DISEASES
  申请人：Ergon Pharmaceuticals LLC

  公开号：EP3287436A1

  公开（公告）日：2018-02-28

  The present invention is directed to compounds and methods that inhibit the cytosolic form of BCAT1.

  本发明涉及抑制 BCAT1 细胞质形式的化合物和方法。
• Compositions and methods of treatment using a BCAT1 inhibitor
  申请人：Ergon Pharmaceuticals, LLC

  公开号：US10941109B2

  公开（公告）日：2021-03-09

  The present invention is directed to compounds and methods that inhibit the cytosolic form of BCAT1.

  本发明涉及抑制 BCAT1 细胞质形式的化合物和方法。
• COMPOUNDS AND COMPOSITIONS FOR USE IN THE TREATMENT OF BCAT1-MEDIATED DISEASES
  申请人：Ergon Pharmaceuticals LLC

  公开号：EP3287436B1

  公开（公告）日：2021-09-29
• COMPOSITIONS AND METHODS OF TREATMENT USING A BCAT1 INHIBITOR
  申请人：Ergon Pharmaceuticals, LLC

  公开号：US20160368862A1

  公开（公告）日：2016-12-22

  The present invention is directed to compounds and methods that inhibit the cytosolic form of BCAT1.