Methyl 3-[2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]ethyl-(3-methoxy-3-oxopropyl)amino]propanoate | 1018686-89-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Methyl 3-[2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]ethyl-(3-methoxy-3-oxopropyl)amino]propanoate
• 英文别名: methyl 3-[2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]ethyl-(3-methoxy-3-oxopropyl)amino]propanoate
• CAS: 1018686-89-9
• 化学式: C₂₂H₃₁N₃O₆S
• 分子量: 465.571
• InChiKey: UPTTZCUTBDKQFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  32
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  114
• 氢给体数：
  1
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  dimethyl 3,3'-((2-aminoethyl)azanediyl)dipropionate 2,2,2-trifluoroacetate 、 丹酰氯 在 potassium carbonate 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 生成 Methyl 3-[2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]ethyl-(3-methoxy-3-oxopropyl)amino]propanoate
  参考文献：
  名称：

  Synthesis and energy-transfer properties of poly(amidoamine) dendrons modified with naphthyl and dansyl groups

  摘要：

  Poly(amidoamine) dendrons of 1-3 generations with naphthyl groups at the periphery and a dansyl group at the focal point were synthesized and carefully characterized. Intramolecular energy-transfer properties of these flexible aliphatic-scaffold light-harvesting dendrons were investigated by UV-vis absorption and fluorescence spectroscopy. Efficient energy transfer from the naphthyl groups to the dansyl group occurred for both the first and the second generation dendrons (the energy-transfer efficiency was 94.3% and 76.9%, respectively), whereas the third generation dendron exhibited a low energy-transfer efficiency of 17.8%. The average donor-acceptor distances between the naphthyl and dansyl groups were calculated for different generation dendrons. Different degrees of the backfolding of dendritic branches were used to interpret the different donor-acceptor distances. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.01.083