苯甲酰胺基-4'-氨基二苯乙烯-2,2'-二磺酸 | 25431-18-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 中文名称: 苯甲酰胺基-4'-氨基二苯乙烯-2,2'-二磺酸
• 英文名称: 4-Benzamido-4'-aminostilbene-2,2'-disulfonate
• 英文别名: 5-amino-2-[(E)-2-(4-benzamido-2-sulfophenyl)ethenyl]benzenesulfonic acid
• CAS: 25431-18-9
• 化学式: C₂₁H₁₈N₂O₇S₂
• 分子量: 474.5
• InChiKey: AFHIIJICYLMCSH-VOTSOKGWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  181
• 氢给体数：
  4
• 氢受体数：
  8

安全信息

• 海关编码：
  2924299090

文献信息

• Lichtpolarisierende Filme oder Folien enthaltende Stilbenfarbstoffe
  申请人：BAYER AG

  公开号：EP0374655A1

  公开（公告）日：1990-06-27

  Lichtpolarisierende Filme oder Folien, vorzugsweise auf Basis eines Vinylalkoholhomo- oder -copolymeren ent­halten Farbstoffe der Formel wobei X und Y die in der Beschreibung angegebenen Bedeutungen haben.

  以乙烯醇均聚物或共聚物为基材的光偏振膜或箔最好含有以下式子的染料 其中 X 和 Y 的含义见说明。
• Lipophilic dye-based FRET assays for clostridial toxin activity
  申请人：ALLERGAN, INC.

  公开号：EP2293064A1

  公开（公告）日：2011-03-09

  Compositions useful for detecting Clostridial toxin activity comprising a cell that comprises a membrane-associated Clostridial toxin substrate comprising a first member of a fluorescence resonance energy transfer pair; and a Clostridial toxin recognition sequence including a cleavage site; and a membrane-associated second member of the FRET pair and methods useful for determining Clostridial toxin activity using such Clostridial toxin substrates.

  用于检测梭状芽孢杆菌毒素活性的组合物，该组合物包含一个细胞，该细胞包含与膜结合的梭状芽孢杆菌毒素底物，该底物包含荧光共振能量转移对的第一位成员；和包括裂解位点的梭状芽孢杆菌毒素识别序列；以及与膜结合的荧光共振能量转移对的第二位成员，以及使用这种梭状芽孢杆菌毒素底物确定梭状芽孢杆菌毒素活性的方法。
• DEVICES FOR BLOOD SAMPLING
  申请人：Seventh Sense Biosystems, Inc.

  公开号：EP3566649A1

  公开（公告）日：2019-11-13

  The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor.

  本发明一般涉及与诊断、治疗和其他应用相关的设备和技术，包括与皮肤相关的应用，例如，用于从受试者（例如，通过皮肤）输送和/或抽取流体的设备。在一些实施例中，该设备包括一个用于从进入部位的受试者皮肤中和/或通过皮肤进入可提取介质的系统，以及一个由支撑结构支撑的压力调节器，该压力调节器能够在进入部位的至少一部分形成跨皮肤的压力差。在某些情况下，该设备还可包括一个由支撑结构支撑的传感器，用于确定可从受试者身上提取的介质的至少一种状况，以及一个由支撑结构支撑的信号发生器，用于产生与传感器确定的介质状况有关的信号。
• Characterization of subvisible particles using a particle analyzer
  申请人：Baxalta Incorporated

  公开号：US10274500B2

  公开（公告）日：2019-04-30

  The present specification discloses methods of characterizing a population of particles using a particle analyzer. Particles may be characterized by size, absolute number, whether the particle is non-proteinaceous or proteinaceous, whether a proteinaceous particle has or lacks a certain physical property, or any combination thereof.

  本说明书公开了使用颗粒分析仪表征颗粒群的方法。颗粒可以通过大小、绝对数量、颗粒是非蛋白质还是蛋白质、蛋白质颗粒是否具有或缺乏某种物理特性或它们的任意组合来表征。
• Techniques and devices associated with blood sampling
  申请人：Seventh Sense Biosystems, Inc.

  公开号：US10939860B2

  公开（公告）日：2021-03-09

  The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor.

  本发明一般涉及与诊断、治疗和其他应用相关的设备和技术，包括与皮肤相关的应用，例如，用于从受试者（例如，通过皮肤）输送和/或抽取流体的设备。在一些实施例中，该设备包括一个用于从进入部位的受试者皮肤中和/或通过皮肤进入可提取介质的系统，以及一个由支撑结构支撑的压力调节器，该压力调节器能够在进入部位的至少一部分形成跨皮肤的压力差。在某些情况下，该设备还可包括一个由支撑结构支撑的传感器，用于确定可从受试者身上提取的介质的至少一种状况，以及一个由支撑结构支撑的信号发生器，用于产生与传感器确定的介质状况有关的信号。