cyclo[1,6-bis(naphthalene dimethylphosphoramidite)] | 847556-68-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: cyclo[1,6-bis(naphthalene dimethylphosphoramidite)]
• 英文别名: cyclo[bis(1,6-naphthylenedimethylamidophosphite)]；3-N,3-N,15-N,15-N-tetramethyl-2,4,14,16-tetraoxa-3,15-diphosphapentacyclo[19.3.1.19,13.05,10.017,22]hexacosa-1(25),5,7,9,11,13(26),17,19,21,23-decaene-3,15-diamine
• CAS: 847556-68-7
• 化学式: C₂₄H₂₄N₂O₄P₂
• 分子量: 466.413
• InChiKey: WQEHBOSJMPUQEK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.85
• 重原子数：
  32.0
• 可旋转键数：
  2.0
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  59.04
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  cyclo[1,6-bis(naphthalene dimethylphosphoramidite)] 在 sulfur 作用下， 以 二氯甲烷 为溶剂， 反应 26.0h， 以79%的产率得到3-N,3-N,15-N,15-N-tetramethyl-3,15-bis(sulfanylidene)-2,4,14,16-tetraoxa-3λ5,15λ5-diphosphapentacyclo[19.3.1.19,13.05,10.017,22]hexacosa-1(25),5,7,9,11,13(26),17,19,21,23-decaene-3,15-diamine
  参考文献：
  名称：

  Cyclic bis-amidophosphites based on 1,6-dihydroxynaphthalene

  摘要：

  将 1,6-二羟基萘与各种三脒亚磷酸酯进行磷酸化，可得到 2:2 环状加合物，萘二基通过脒基亚磷酸酯桥实现 1,6′,1′,6-键连接。

  DOI：

  10.1007/s11172-013-0293-9
• 作为产物：
  描述：

  1,6-二羟基萘 以 乙腈 为溶剂， 生成 cyclo[1,6-bis(naphthalene dimethylphosphoramidite)]
  参考文献：
  名称：

  Dismutation of arylene phosphorodiamidites: Specific features and aspects of preparative use

  摘要：

  The dismutation ofarylene phosphorodiamidites derived from the simplest phenols and naphthols and of their dibasic analogs was studied. The main regular trends of this process and the limits of its synthetic applicability were determined.

  DOI：

  10.1134/s1070363206020046

文献信息

• 2,6- and 1,6-Dihydroxynaphthalenes in the Synthesis of Phosphacyclophanes
  作者：E. N. Rasadkina、P. V. Slitikov、M. S. Mel'nik、A. I. Stash、V. K. Bel'skii、E. E. Nifant'ev

  DOI：10.1023/b:rugc.0000045868.37162.87

  日期：2004.7

  Peculiar phosphacyclophanes were prepared from symmetrical 2,6- and unsymmetrical 1,6-dihydroxynaphthalenes. The position of the hydroxy groups in dihydroxynaphthalenes considerably affects their reactivity, the structure of the phosphacyclophanes obtained, and also the disproportionation of bisphosphoramidites. Oxo and thio derivatives of these phosphoramidites as well as their molybdenum complexes were prepared.